> My Geno 2.0 result for PF3514 also shows > AG, but this probably means nothing since my C would not have been > detectable by the Geno 2.0 chip if it is looking for A or G. I think it is > possible that PF3514 was erroneously reported by Paolo Francalacci as A to > G instead of A to C, especially since both PF3514 and Y1850 (FGC2408) are > shown by the ISOGG Y Browser to be located at the IJ level in the Y tree. So does this mean that all the Geno 2.0 results for PF3514+ might be mistaken and are reading AG when they should be reading CC and that the few anomalous AA results for I1 people are also mistaken and should be reading CC in that location? Matthew Simonds > Date: Fri, 3 Jan 2014 14:13:11 -0600 > From: [email protected] > To: [email protected] > Subject: Re: [yDNAhgI] PF3514 > > My Full Genomes result also shows me to be FGC2408+; i.e, A to C at > location 5578819 of the Y. All 76 of my reads at this location show C, so > the result seems quite reliable. My Geno 2.0 result for PF3514 also shows > AG, but this probably means nothing since my C would not have been > detectable by the Geno 2.0 chip if it is looking for A or G. I think it is > possible that PF3514 was erroneously reported by Paolo Francalacci as A to > G instead of A to C, especially since both PF3514 and Y1850 (FGC2408) are > shown by the ISOGG Y Browser to be located at the IJ level in the Y tree. > > > On Fri, Jan 3, 2014 at 11:35 AM, John O'Grady <[email protected]>wrote: > > > There are two SNPs at the same position. PF3514 is A to G. Y1850 is A to C. > > Geno 2.0 shows me as AG. Full Genomes shows me as CC, and calls the SNP > > FGC2408, which is the same as Y1850. > > Anyone who has AG in Geno 2.0 is probably actually CC and Y1850/FGC2408. > > John O'Grady > > > > > > > > There is something erratic about the behavior of PF3514. I show 5 I1 > > plus > > > one I2 with AA, while many dozens of others are all AG. But those 5 > > > anomalies in I1 are from very different parts of the I1 tree; their > > results > > > can not be due to an inherited common mutation in their ancestral lines. > > > > > > Kenneth Nordtvedt > > > > > > > > ------------------------------- > > To unsubscribe from the list, please send an email to > > [email protected] with the word 'unsubscribe' > > without the quotes in the subject and the body of the message > > > > ------------------------------- > To unsubscribe from the list, please send an email to [email protected] with the word 'unsubscribe' without the quotes in the subject and the body of the message

Matthew, I think that is most likely to be the case for I1 and I2 people. At least I don't think the Geno 2.0 chip is capable of reading C at this location. On Fri, Jan 3, 2014 at 3:18 PM, Matthew Simonds <[email protected]>wrote: > > > My Geno 2.0 result for PF3514 also shows > > AG, but this probably means nothing since my C would not have been > > detectable by the Geno 2.0 chip if it is looking for A or G. I think it > is > > possible that PF3514 was erroneously reported by Paolo Francalacci as A > to > > G instead of A to C, especially since both PF3514 and Y1850 (FGC2408) are > > shown by the ISOGG Y Browser to be located at the IJ level in the Y tree. > > > > So does this mean that all the Geno 2.0 results for PF3514+ might be > mistaken and are reading AG when they should be reading CC and that the few > anomalous AA results for I1 people are also mistaken and should be reading > CC in that location? > > Matthew Simonds > > > > > Date: Fri, 3 Jan 2014 14:13:11 -0600 > > From: [email protected] > > To: [email protected] > > Subject: Re: [yDNAhgI] PF3514 > > > > My Full Genomes result also shows me to be FGC2408+; i.e, A to C at > > location 5578819 of the Y. All 76 of my reads at this location show C, so > > the result seems quite reliable. My Geno 2.0 result for PF3514 also shows > > AG, but this probably means nothing since my C would not have been > > detectable by the Geno 2.0 chip if it is looking for A or G. I think it > is > > possible that PF3514 was erroneously reported by Paolo Francalacci as A > to > > G instead of A to C, especially since both PF3514 and Y1850 (FGC2408) are > > shown by the ISOGG Y Browser to be located at the IJ level in the Y tree. > > > > > > On Fri, Jan 3, 2014 at 11:35 AM, John O'Grady <[email protected] > >wrote: > > > > > There are two SNPs at the same position. PF3514 is A to G. Y1850 is A > to C. > > > Geno 2.0 shows me as AG. Full Genomes shows me as CC, and calls the SNP > > > FGC2408, which is the same as Y1850. > > > Anyone who has AG in Geno 2.0 is probably actually CC and > Y1850/FGC2408. > > > John O'Grady > > > > > > > > > > > There is something erratic about the behavior of PF3514. I show 5 I1 > > > plus > > > > one I2 with AA, while many dozens of others are all AG. But those 5 > > > > anomalies in I1 are from very different parts of the I1 tree; their > > > results > > > > can not be due to an inherited common mutation in their ancestral > lines. > > > > > > > > Kenneth Nordtvedt > > > > > > > > > > > > ------------------------------- > > > To unsubscribe from the list, please send an email to > > > [email protected] with the word 'unsubscribe' > > > without the quotes in the subject and the body of the message > > > > > > > ------------------------------- > > To unsubscribe from the list, please send an email to > [email protected] with the word 'unsubscribe' > without the quotes in the subject and the body of the message > > > ------------------------------- > To unsubscribe from the list, please send an email to > [email protected] with the word 'unsubscribe' > without the quotes in the subject and the body of the message >