In 1808 Franklin Wise came to Jackson Co. In 1855 Isaac Wise and George Wise came to Jackson Co. - "Early settlers and their contribution to Jackson Co. and it's county seat, Ripley, WV" ISAAC WISE was born March 12, 1818 in Morgantown, Monongalia Co., VA, and died December 19, 1908 in Syracuse, Meigs Co., Ohio. He married ELIZABETH MCCULLOUGH. She was born March 14, 1817 in PA, and died January 10, 1887 in Wirt Co., WV. In October 1869 John purchased 40 acres from Dixon R. King, for $200, in Grant Township, Cavins Fork of Pond Creek, Jackson Co. GEORGE WASHINGTON WISE, son of Isaac and Elizabeth, was born March 12, 1841. He married (1) MARY ELLEN CROSS August 19, 1865 in Jackson Co., WV, daughter of ISAAC CROSS and MARY BUCKLEY. She was born Abt. 1847 in Jackson Co., WV, and died January 06, 1877 in Jackson Co., WV. He married (2) ELIZABETH JACKMAN September 28, 1878 in Jackson Co., WV, daughter of JOHN JACKMAN and NANCY MCCONNELL. She was born September 09, 1834 in Carroll Co., Ohio. Isaac moved his family to Wirt Co. after 1870. After the death of Elizabeth, he moved to the home of his daughter, Nancy Wise Blake, Meigs Co., Ohio.