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    1. Re: [WELLS] mutations
    2. One DNA group has two brothers with one marker difference between them. It was one of those fast mutations that happened between the birth of the older brother and the younger brother. The rest of the 37 markers are exact. I can't remember if it is the Wells group or the Carter group, does anyone else remember this? Kathy Wells ----- Original Message ----- From: "Leslie W Wells" <[email protected]> To: <[email protected]> Sent: Friday, July 24, 2009 8:48 AM Subject: [WELLS] mutations > Orin, > > Regarding baseline family W006 it seems that two lines of descent are > marked by mutations. You had mentioned that Roberts descendants were > distinguished by a mutation on DYS437 and yesterday I was reading a post > that might indicate that Nathan's descendants may also be recognized by a > mutation on DYS452. My question is do we have any idea how far up the > tree these mutations run, with which generation do they originate? Thanks > so much for your time. > > Leslie. > > > > ------------------------------- > To unsubscribe from the list, please send an email to > [email protected] with the word 'unsubscribe' without the quotes > in the subject and the body of the message

    07/25/2009 03:08:46
    1. Re: [WELLS] mutations
    2. Mail Lists
    3. Kathy This is not as uncommon as you think. In my group, in both branches, we have a number of mutations between brothers and father-son. Currently we are waiting for SMGF results to see if these mutations are transient or not. They could be environmental and not pass on. Also, if environmentally caused, was it before or after offspring is a factor. In all cases so far, every mutation has been on different markers: 389ii, 442, 463, and Gata A10. All have been only a single mutation with a single change in value. I am not sure what you mean by fast mutations. Depending upon whose analysis, some claim markers change at different rates. This is a highly disputed area where too little data has been obtained so far. Several more generations of people are needed to resolve the statistics. Right now, the best samples we have cover 3 generations - grandfather, father, and son. Going back in time, we have to extrapolate the patterns from multiple lines with proven genealogies. Based upon those results, we can estimate the pattern for the common ancestor, and the descendants down to the tested persons. It is possible a mutation or 2 could have happened that carried across all family lines, even in different generations. > One DNA group has two brothers with one marker difference between them. > It > was one of those fast mutations that happened between the birth of the > older > brother and the younger brother. The rest of the 37 markers are exact. > I > can't remember if it is the Wells group or the Carter group, does anyone > else remember this? > Kathy Wells >

    07/25/2009 03:15:48