We have a case where two brothers differ by three markers. One is two markers different from his father and the other one marker different. Each on different markers. Mutations can happen at any time. Just because there is a mutation or one can not declare the marker to be a "fast" mutation or "fast moving marker". I believe that this has been done too often. Just because the existing research has declared most markers can be expected to mutate (change value) on replication once every 500 generations (0.002 chance at every birth/replication) does not mean that it will happen like clockwork. A given marker may alter more frequently or less frequently. And from what we have seen in the Wells study it may happen more or less frequently in specific families. The more important aspect of this to us is has it happened? When it does it can help us isolate specific branches of a family. Unfortunately, it does not happen often enough to give us a lot of help in most situations. At 07:08 AM 7/25/2009, [email protected] wrote: >One DNA group has two brothers with one marker difference between them. It >was one of those fast mutations that happened between the birth of the older >brother and the younger brother. The rest of the 37 markers are exact. I >can't remember if it is the Wells group or the Carter group, does anyone >else remember this? > Kathy Wells > > > >----- Original Message ----- >From: "Leslie W Wells" <[email protected]> >To: <[email protected]> >Sent: Friday, July 24, 2009 8:48 AM >Subject: [WELLS] mutations > > > > Orin, > > > > Regarding baseline family W006 it seems that two lines of descent are > > marked by mutations. You had mentioned that Roberts descendants were > > distinguished by a mutation on DYS437 and yesterday I was reading a post > > that might indicate that Nathan's descendants may also be recognized by a > > mutation on DYS452. My question is do we have any idea how far up the > > tree these mutations run, with which generation do they originate? Thanks > > so much for your time. > > > > Leslie. > > > > > > > > ------------------------------- > > To unsubscribe from the list, please send an email to > > [email protected] with the word 'unsubscribe' without the quotes > > in the subject and the body of the message > > >------------------------------- >To unsubscribe from the list, please send an email to >[email protected] with the word 'unsubscribe' without the >quotes in the subject and the body of the message Orin R. Wells Wells Family Research Association P. O. Box 5427 Kent, Washington 98064-5427 <[email protected]> http://www.wells.org Subscribe to the "Wells-L" list on RootsWeb