Linda,   If you ever see that sale again, please let the list know immediately, certain there are several of us who would jump at the chance of the test. When you mentioned it telling of the Crohns gene, really hit home for me, as I have had the problem since 1971, took several years to learn there was a gene for it.  I haven't found anyone on my father's Shanks side who has had it, that is my Scotch Irish, they came from Belfast in 1767 to Charleston, S. Carolina for a land offering. My husband has had his DNA done with the Family Tree dna with his Widener list, but only told of his paternal lines.  What you spoke of told so much more than we have received from them. Thanks for all of your help!! Mary Widener -------------------------------

Linda - please remind us all again about how to get a DNA test. Thanks, Karen ----- Original Message ----- From: "Mary Widener" <[email protected]> To: <[email protected]> Sent: Tuesday, May 25, 2010 8:13 PM Subject: [S-I] DNA\ Linda, If you ever see that sale again, please let the list know immediately, certain there are several of us who would jump at the chance of the test. When you mentioned it telling of the Crohns gene, really hit home for me, as I have had the problem since 1971, took several years to learn there was a gene for it. I haven't found anyone on my father's Shanks side who has had it, that is my Scotch Irish, they came from Belfast in 1767 to Charleston, S. Carolina for a land offering. My husband has had his DNA done with the Family Tree dna with his Widener list, but only told of his paternal lines. What you spoke of told so much more than we have received from them. Thanks for all of your help!! Mary Widener ------------------------------- ------------------------------- To unsubscribe from the list, please send an email to [email protected] with the word 'unsubscribe' without the quotes in the subject and the body of the message

Hi Mary, I will let the list know. I think the announcement came on the ISOGG list.... There's a number of Crohn's genes -- see the pages at www.23andme.com ....I just learned this myself today! Maybe even more involved...they seem to update dynamically, so I had new stuff posted even today. I would have to say that even at $500 the testing is worth it. Besides all mentioned here, you also find out how you react to various medications. See here: https://www.23andme.com/health/drugs/ This is information that your doctor can use TODAY to ensure you get better medical treatment. I learned I am at increased risk for adverse reactions to anesthesia -- and some people posted comments who also have the gene and said it was totally true for them. I can warn my doctor. I have an increased risk of developing neuropathy if taking certain statins. Again, I can avoid these or watch more carefully. I would tolerate a normal dosage of wafarin -- but some people take as little as a 4th a normal dose. You can bleed to death if you are overdosed. I was astounded at what I learned. The studies that established these results are duly noted, should my doctor wish to study the information. Additional studies might show the initial ones were wrong, of course. The medical information was far more interesting than the genealogy -- and frankly, well worth $500, if you have it. This information could save my life someday and gives me peace of mind today. I am not likely to die of breast cancer (no genes increasing my risk above the average) but type 2 diabetes? Yup. So I better get more serious about dieting. Now, or I'll end up like my dad, who has it. Very motivating......I could have spent much more at the doctors and learned far less about my health risks. You also learn if you carry certain diseases. Not me, so far. I seem to have pretty good genes, except for the gut and liver genes, which are not good. Linda Merle ----- Original Message ----- From: "Mary Widener" <[email protected]> To: [email protected] Sent: Tuesday, May 25, 2010 8:13:09 PM GMT -05:00 US/Canada Eastern Subject: [S-I] DNA Linda, If you ever see that sale again, please let the list know immediately, certain there are several of us who would jump at the chance of the test. When you mentioned it telling of the Crohns gene, really hit home for me, as I have had the problem since 1971, took several years to learn there was a gene for it. I haven't found anyone on my father's Shanks side who has had it, that is my Scotch Irish, they came from Belfast in 1767 to Charleston, S. Carolina for a land offering. My husband has had his DNA done with the Family Tree dna with his Widener list, but only told of his paternal lines. What you spoke of told so much more than we have received from them. Thanks for all of your help!! Mary Widener ------------------------------- ------------------------------- To unsubscribe from the list, please send an email to [email protected] with the word 'unsubscribe' without the quotes in the subject and the body of the message

I wish these tests had been around a little earlier when there was still someone in my parent's generation to test, and someone in my generation other than myself. My daughter has Crohn's. It affected her lower intestine, which had to be removed over ten years ago. She is one of the lucky few to have been a good candidate for a Koch pouch, not usually possible for Crohn's patients. No one on either side of our family in any known generation has had this auto-immune disease. My husband died of multiple myeloma, which hasn't so far been identified as either autoimmune or hereditary. My dad's mother was SI (Warnock) with a dollop of English (Milner); his father was English (Wilmoth, Sargent) with a smidgen of Dutch (Walraven). My dad had a congenital heart defect, and his doctor, way back in 1902 when he was 20, gave him about 10 years to live and recommended a low-fat diet. Dad was a chef and prepared nearly all of our meals, so we were on his low-fat regimen for years before that idea was widely accepted. He died of a heart attack at 80. My mom, active and healthy all her life, died of a massive cerebral hemorrhage at 79. Her mother was Norwegian (Johnson) & English (York); her dad was German (Otto & Rowe). Both my parents were mentally sharp until their deaths. On my husband's side, his dad was German (Beck), English (Neil) & French-speaking Swiss (Kaufman); his mom was Scot (Stevenson) & English (Haskit). They each died after a series of strokes (due, perhaps, to their high-fat diet) at ages 73 and 75. "Pop" developed senile dementia about 8 years before his death. "Mom" remained mentally alert all her life. I did fairly well in the gene pool. At 90, my main problem is osteo-arthritis. I had knee replacements ten years ago, which helped a lot, but spinal involvement limits my ability to walk any distance and my sense of balance is a bit unreliable. On a trip to Greece & Crete a couple of years ago I used a three-wheel walker for sightseeing and, with a little help, managed the climb at the Parthenon and Delphi. A couple of years ago my kidney function started to sag off, requiring a low phosphorus diet, and last year I had a fleeting TIA episode, which prompted my doctor to put me on daily baby aspirin, cholesterol & blood pressure meds. I still garden, cook and have a busy social agenda with family & friends. I'm looking forward in June & July to a month in the high Sierras with my daughter & son-in-law. We'll be "camping" in an RV, so that's not exactly roughing it. And although I can no longer wade the creeks with a fly-rod or sit for long in a boat, I can still cast a line for trout from the banks of those beautiful lakes. Virginia -----Original Message----- From: [email protected] [mailto:[email protected]] On Behalf Of [email protected] Sent: Tuesday, May 25, 2010 7:03 To: [email protected] Subject: Re: [S-I] DNA Hi Mary, I will let the list know. I think the announcement came on the ISOGG list.... There's a number of Crohn's genes -- see the pages at www.23andme.com ....I just learned this myself today! Maybe even more involved...they seem to update dynamically, so I had new stuff posted even today. Linda Merle