I have encountered the Frederick Wise to whom you refer, his widow, and children in my research. I have been trying to figure out if there was a relationship with my Wise family. I know the Court appointed a Frederick Wise as the Guardian of the Deceased Frederick's children. I did not know the Deceased had a father also named Frederick. If my memory serves me, the deceased and his widow were probably the age of my Henry Wise's children, so does that mean the grandfather of the children, Frederick Wise was possibly a sibling to my Henry Wise? I believe they may be possibly be related, also to a George Wise who was a farmer in an outlying district of Greensburg. I say this because John H. Wise was some how involved in the real estate of the George Wise. I have not concentrated on these possible relationships because I have been trying to find my Henry Wise's parents. My family oral history states the Wise ancestors migrated "from VA near the water, to the PA mountains! where he and his bride raised 14 children." If my Wise family members were not Gamblers in land speculation, they were a well financed family because they had substantial real estate in Westmoreland County and Jefferson County, PA. I have not had the time to check the surrounding counties to see if they had any land in those jurisdictions. This is the time line of my Henry Wise family: Gen. I....Henry Wise born 1763- died 1831 married Barbara Rohrer Gen. II...#1. John H. Wise born (know but date not handy)....died 1833 (not found any marriage or children for John H. Wise...many, many real estate transactions over the years.) He served in the War of 1812 as a Lieutenant, was active in the local Militia and was known as General John H. Wise. He served in the PA State Legislature in early 1800's. Gen. II...#2. Frederick A. Wise born in Greensburg, .....died in Missouri. His Probate records and will can be viewed on the web via the Missouri on line records. He served in the War of 1812 as a Lieutenant. He was the publisher of one of the Greensburg newspapers. He moved to Palmyra, Missouri with his entire family. He started a newspaper there that lasted for two years. He then moved to St. Louis County where he farmed. I thought he was the Guardian of the Deceased children, but now that you tell me the deceased Frederick Wise had a father named Frederick, perhaps the Guardian of those children was their Grandfather. Gen. II...#3 Jacob Michael Wise married Margaret Covode Williams. He was an attorney, he also had many real estate transactions. He replaced his brother John H. Wise in the PA State Legislature. Their combined time holding the seat was I believe, 20 years. Gen. II...#4 Mary Wise. I had not been able to find her, but recently a researcher of the Rohrer family has told me that she married a gentleman named Saylor. I have not had the opportunity to review his findings. I would think the Westmoreland County, PA Orphans Court Records might be a place to learn about the deceased Frederick Wise family since the children's estate was over seen by that court for a long time. If my recall is right, the children were quite young when their father died. I hope this helps. Shirley