This is a Message Board Post that is gatewayed to this mailing list. Classification: Query Message Board URL: http://boards.ancestry.com/mbexec/msg/rw/2YB.2ACI/1225.1237.1379.1.1.1.1 Message Board Post: My grandmother also died of Parkinson's. My mother, her dtr, has supranuclear palsy. I wonder if both are not further mutations of Machado-Joseph's disease. Maybe someday scientists will be able to tell us. Good luck, NancyS