I had searched for information of an epidemic in the Pittsburgh Pa area around 1845 when my gr gr gr grnadmother and two daughters died of Smallpox. None of the official listings of epidemics mention this time frame. It wasn't until I searched the Digital holdings of Historic Pittsburgh searching for Smallpox in 1845 that I found out there had been an outbreak in the area the winter of 1845-1846. It wasn't announced as an epidemic merely an outbreak. Laurie Beth Roman