Boy that sure hit the nail on the head. I had taken Advil with some relief, but it soon became not enough and I finally asked the doctor for something. After she heard the family history of arthritis she gladly gave me something. I take Celebrex 200mg twice a day. There are many days that is not enough and I was told to take Arthritis strength Tylenol. The weather changes are just terrible. Thanks for sharing, I appreciate it very much. Jackie