There was an interesting article today on BBC about the effect the age of the father has on DNA mutations. See: http://www.bbc.co.uk/news/health-19336438 A key point was: "The results indicate that a father aged 20 passes, on average, approximately 25 mutations, while a 40-year-old father passes on about 65. The study suggests that for every year a man delays fatherhood, they risk passing two more mutations on to their child." I recently noted this subject to Don and Sue. My line has perhaps the most mutations in Group A and this seems to ring true with us. The ages are as follows: gg grandfather | 49 years old g grandfather | 54 years old grandfather | 23 years old father | 41 years old me Some of my related lines have even older links. Best wishes! Peter

I was about to comment on this myself. Unfortunately, no one says which genes might be affected. All of them? We only test a tiny subset for DNA ancestry analysis. What intrigues me is that I have a single "odd" difference in one of my markers relative to other C-2 members. Actually, like A, more than one of us do, but we still cluster clearly on the others. Intrigued because my great great grandfather born in 1833 in Adams county Ohio was the last sibbling born out of perhaps as many as 10. That would make his father rather old, no? No way to know, when a single mutation occurred unless we have data from say the 1st or 2nd born male sibbling from the same father. Still, it suggests we have to be skeptical about single differences, especially one's that are supposedly not as stable in general. Larry (Don) Kincaid, Group C-2 On Thu, Aug 23, 2012 at 12:16 PM, Kincaid <7kincaid@nb.sympatico.ca> wrote: > There was an interesting article today on BBC > about the effect the age of the father has on > DNA mutations. See: > > http://www.bbc.co.uk/news/health-19336438 > > A key point was: "The results indicate that a father > aged 20 passes, on average, approximately 25 mutations, > while a 40-year-old father passes on about 65. The study > suggests that for every year a man delays fatherhood, they > risk passing two more mutations on to their child." > > I recently noted this subject to Don and Sue. My > line has perhaps the most mutations in Group A > and this seems to ring true with us. The ages > are as follows: > > gg grandfather > | 49 years old > g grandfather > | 54 years old > grandfather > | 23 years old > father > | 41 years old > me > > Some of my related lines have even older links. > > Best wishes! > > Peter > > > For complete information about the Kincaid of all spellings DNA project, > including a chart, lineages, and how to participate, go to: > > www.kincaiddna.org > > > > > > ------------------------------- > To unsubscribe from the list, please send an email to > KINCAID-request@rootsweb.com with the word 'unsubscribe' without the > quotes in the subject and the body of the message > -- dddddddd