Note: * means the epidemic was spread over more than one year. WW means World Wide YearAilmentPlaceOther info 1350Bubonic plagueWW* 1499Bubonic plagueUK London- 1507"Fever"UK* 1507-51 1551InfluenzaUK- 1555FamineUKRains brought famine & weakness 1556Bubonic plagueUK* 1556-63 Extreme 1578Bubonic plagueUK- 1586Bubonic plagueUK* Chesterfield. Harvest failed 1591Acute distressUK- 1593Bubonic plagueUK- 1596FamineUK* Harvests failed & epidemics 1603Bubonic plagueUK- 1612Bubonic plagueUK- 1617SmallpoxUS* Native Americans 1623Bad yearsUK* 2 years 1625Bubonic plagueUK- 1626Bubonic plagueUK- 1630Very bad yearUKMany died 1631Bubonic plagueUK- 1633SmallpoxUS* Native Americans 1636Bubonic plagueUK- 1637Bubonic plagueUK- 1647Yellow FeverWest Indies- 1648SmallpoxUS- 1648Whooping coughUS- 1654Bubonic plagueUK- 1657MeaslesUS-Boston- 1662SmallpoxUS-NY- 1665Bubonic plagueUK* Extreme 1668Yellow FeverUS-NY- 1677SmallpoxUS-Boston* 1687MeaslesUS-Boston- 1690Yellow FeverUS-NY- 1699Yellow FeverUS-SC- 1702Yellow FeverUS-NY* 1702Scarlet FeverUS-Boston- 1706Yellow FeverUS-SC- 1713MeaslesUS-Boston- 1721SmallpoxUS-Boston- 1723InfluenzaWW- 1723FamineUK* 7 years poor harvests & epidemics 1728Yellow FeverUS-SC- 1729MeaslesUS-Boston- 1732Yellow FeverUS-SC- 1732InfluenzaWW* 1735Diphtheria/scarlet feverUS* 4 yrs - New England 1738SmallpoxUS-SC- 1739MeaslesUS-Boston* 1743Yellow FeverUS-NY* 1747MeaslesUS-CT, NY, PA, SC- 1759MeaslesNorth America- 1761InfluenzaUS & West Indies- 1763SmallpoxUS-Boston* 1772MeaslesUS- 1775InfluenzaWW* 1783Bilious disorderUSFatal 1788MeaslesUS-PA, NY- 1789InfluenzaUS- 1792Yellow FeverUS* 7 yrs 1793UnknownUS-PA- 1793InfluenzaUS-VT, VA- 1802SmallpoxUS-NE- 1803Yellow FeverUS-NY- 1820"Fever"US* 1826CholeraWW* 1826-37 1826Dengue FeverUS and West Indies* 1829MalariaUS* 1831CholeraUK, US-OH, NY* Started WW 1826 1832InfluenzaUS- 1837TyphusUS-PA- 1837SmallpoxUS-Native Americans- 1841Yellow FeverUS- 1847MeaslesUS-Native Americans- 1847Yellow FeverUS-New Orleans- 1847InfluenzaWW* 1848CholeraWW* 1850Yellow FeverUS- 1850InfluenzaUS* 1850Dengue FeverUS* 1851CholeraUS-IL- 1852Yellow FeverUS-New Orleans- 1853CholeraBirmingham? This came from a UK report with the ?- 1855Yellow FeverUS- 1857InfluenzaWW* 1860SmallpoxUS-PA- 1861Numerous EpidemicsUS-Civil war numerous infectious diseases* 1865SmallpoxUS* 1865CholeraUS- 1865TyphusUS* 1868SmallpoxUS* 7 yrs 1873InfluenzaUK, US & Europe* 1873CholeraUS- 1878Yellow FeverUS-New Orleans- 1885TyphoidUS-PA- 1886Yellow FeverUS-FL- 1889InfluenzaWW* 1893PolioUS1st known outbreak 1900PlagueUS* 1901SmallpoxUS* 1907PolioUS* 9 yrs. 1917InfluenzaWW* Worst ever 1931PolioUS* 1931 to 1942, 11 yrs