List A lot of people will be interested to see this paper - a free download at: http://www.cell.com/current-biology/fulltext/S0960-9822(17)31091-6 "Genetic Discontinuity between the Maritime Archaic and Beothuk Populations in Newfoundland, Canada" Ana T. Duggan, et al. This group of researchers has produced a set of 26 complete mtDNA sequences: from Haplogroups A, B, C, D & X; and about 50 other partial mtDNA sequences. The Summary of the paper is given below., together with an analysis of the complete genomes. The details of all the sequences is to be found on the EXCEL spreadsheet which is part of the supplementary material accompanying the paper. As usual I have added the complete sequences to my 'Checker' program to ensure accuracy of transcription. Ian www.ianlogan.co.uk -------------------------- Summary Situated at the furthest northeastern edge of Canada, the island of Newfoundland (approximately 110,000 km2) and Labrador (approximately 295,000 km2) today constitute a province characterized by abundant natural resources but low population density. Both landmasses were covered by the Laurentide ice sheet during the Last Glacial Maximum (18,000 years before present [YBP]); after the glacier retreated, ice patches remained on the island until ca. 9,000 calibrated (cal) YBP [1]. Nevertheless, indigenous peoples, whose ancestors had trekked some 5,000 km from the west coast, arrived approximately 10,000 cal YBP in Labrador and ca. 6,000 cal YBP in Newfoundland [2, 3]. Differential features in material culture indicate at least three settlement episodes by distinct cultural groups, including the Maritime Archaic, Palaeoeskimo, and Beothuk. Newfoundland has remained home to indigenous peoples until present day with only one apparent hiatus (3,400–2,800 YBP). This record suggests abandonment, severe constriction, or local extinction followed by subsequent immigrations from single or multiple source populations, but the specific dynamics and the cultural and biological relationships, if any, among these successive peoples remain enigmatic [4]. By examining the mitochondrial genome diversity and isotopic ratios of 74 ancient remains in conjunction with the archaeological record, we have provided definitive evidence for the genetic discontinuity between the maternal lineages of these populations. This northeastern margin of North America appears to have been populated multiple times by distinct groups that did not share a recent common ancestry, but rather one much deeper in time at the entry point into the continent. -------------------------- MF588810(Canada-ancient-BTK141) Duggan Haplogroup C1b 12-OCT-2017 A73G T236C A248G A263G A290- A291- T489C A493G C522- A523- A750G A1438G A2706G T3552A A4715G A4769G T4967C C7028T C7196A G8584A A8701G A8860G T9540C A9545G T10031C A10398G C10400T T10873C G11719A G11914A C12705T A13263G T14318C C14766T T14783C G15043A A15061G G15301A A15326G A15487T C16223T T16298C T16325C C16327T T16519C MF588811(Canada-ancient-BTK142) Duggan Haplogroup A2 12-OCT-2017 C64T A73G T146C A153G A235G A263G 309.1C 315.1C C522- A523- A663G A750G A1438G G1719A A1736G A2706G T4248C A4769G A4824G C7028T G8027A C8794T A8860G C11665T G11719A G12007A C12705T C14766T A15326G T16086C C16111T C16223T C16290T G16319A T16356C T16362C MF588812(Canada-ancient-BTK144) Duggan Haplogroup C1b 12-OCT-2017 A73G A263G A290- A291- T489C A493G C522- A523- A750G A1438G A2706G T3552A A4715G A4769G C7028T C7196A G8584A A8701G A8860G T9540C A9545G T10031C A10398G C10400T T10873C G11719A G11914A C12705T A13263G T14318C C14766T T14783C G15043A G15301A A15326G A15487T C16223T C16266T A16293C T16298C T16325C C16327T T16519C MF588813(Canada-ancient-BTK146) Duggan Haplogroup C1b 12-OCT-2017 A73G T236C A263G A290- A291- T489C A493G C522- A523- A750G A1438G A2706G T3552A A4715G A4769G T4967C C7028T C7196A G8584A A8701G A8860G T9540C A9545G T10031C A10398G C10400T T10873C G11719A G11914A C12705T A13263G T14318C C14766T T14783C G15043A A15061G G15301A A15326G A15487T C16223T T16298C T16325C C16327T T16519C MF588814(Canada-ancient-BTK147) Duggan Haplogroup A2 12-OCT-2017 C64T A73G T146C A153G T195C A235G A263G 309.1C 315.1C C522- A523- A663G A750G A1438G G1719A A1736G A2706G T4248C A4769G A4824G C7028T G8027A C8794T A8860G G11719A G12007A C12705T C14766T A15326G C16223T C16290T G16319A T16362C MF588815(Canada-ancient-BTK-150) Duggan Haplogroup C4c1 12-OCT-2017 A73G G143A A263G 309.1C 315.1C T489C A750G T1243C A1438G 2232.1A A2706G T3552A A4715G A4769G G6026A C7028T C7043T T7064C C7196A G8584A A8701G A8860G T9540C A9545G A10398G C10400T T10873C G11719A G11914A G11969A C12705T A13263G T14318C C14433T C14766T T14783C G15043A G15148A T15204C G15301A A15326G A15487T C16223T T16298C C16327T T16519C MF588816(Canada-ancient-BTK151) Duggan Haplogroup C1c 12-OCT-2017 A73G A263G A290- A291- 309.1C 315.1C T489C A750G A1438G G1888A A2706G T3552A A4715G A4769G T5201C C7028T C7196A G8584A A8701G A8860G T9540C A9545G A10398G C10400T T10873C T11087C G11719A G11914A C12705T A13263G T14318C C14766T T14783C G15043A G15301A A15326G A15487T G15930A C16223T T16298C T16325C C16327T MF588817(Canada-ancient-BTK153) Duggan Haplogroup B2c 12-OCT-2017 A73G A263G 309.1C 309.2C 315.1C G499A 523.1C 523.2A 523.3C 523.4A A750G A827G A1438G A2706G A3547G A4769G G4820A T4977C C6473T C7028T A7241G C8281- C8282- C8283- C8284- C8285- T8286- C8287- T8288- A8289- A8860G T9950C C11177T G11719A A11930G G13590A C14766T A15326G C15535T A16182- A16183- T16189C 16193.1C 16193.2C T16217C T16519C MF588823(Canada-ancient-BTk166) Duggan Haplogroup B2c 12-OCT-2017 A73G A263G 309.1C 309.2C 315.1C G499A 523.1C 523.2A 523.3C 523.4A A750G A827G A1438G A2706G A3547G A4769G G4820A T4977C C6473T C7028T A7241G C8281- C8282- C8283- C8284- C8285- T8286- C8287- T8288- A8289- A8860G T9950C C11177T G11719A A11930G G13590A C14766T A15326G C15535T A16182- A16183- T16189C 16193.1C 16193.2C T16217C T16519C MF588826(Canada-ancient-BTK178) Duggan Haplogroup X2a1 12-OCT-2017 A73G G143A A153G T195C A200G A263G 315.1C A750G A1438G G1719A A2706G T3552C A4769G T6221C C6371T C7028T A8860G A8913G G11719A A12397G C12705T A13966G T14470C T14502C C14766T A15326G T16093C A16183- T16189C 16193.1C G16213A C16223T C16278T T16519C MF588829(Canada-ancient-BTK189) Duggan Haplogroup X2a1b 12-OCT-2017 A73G G143A A153G T195C A200G A263G 309.1C 315.1C A750G A1438G G1719A A2706G T3552C A4769G T6221C C6371T C7028T A8422G A8860G A8913G G11719A C11932T A12397G C12705T A13966G T14470C T14502C C14766T T15001C A15326G T16093C A16183- T16189C 16193.1C G16213A C16223T C16278T T16519C MF588830(Canada-ancient-BTK190) Duggan Haplogroup C1c 12-OCT-2017 A73G C150T T152C A263G A290- A291- 315.1C T489C A750G A1438G G1888A A2706G T3552A A4702G A4715G A4769G C7028T C7196A G8584A A8701G A8860G T9540C A9545G A10398G C10400T T10873C G11719A G11914A C12705T A13263G T14318C C14766T T14783C C15007T G15043A G15301A A15326G A15487T G15930A C16223T T16298C T16325C C16327T MF588833(Canada-ancient-BTK36) Duggan Haplogroup X2a1 12-OCT-2017 A73G G143A A153G T195C A200G A263G 315.1C A750G A1438G G1719A A2706G T3552C A4769G T6221C C6371T C7028T A8860G A8913G G11719A A12397G C12705T A13966G T14470C T14502C C14766T A15326G A16183- T16189C 16193.1C G16213A C16223T C16278T T16519C MF588834(Canada-ancient-BTK37) Duggan Haplogroup D1 12-OCT-2017 A73G A263G C285T 315.1C T489C A750G A1438G C2092T A2706G G3010A A3805G A4769G C4883T C5178A C7028T C7747T T8022C C8414T A8701G A8860G T9540C A10398G C10400T T10873C G11719A A11959G C12705T C14668T C14766T T14783C G15043A G15301A A15326G C15760T C16223T T16325C T16362C MF588838(Canada-ancient-BTK41) Duggan Haplogroup C1b 12-OCT-2017 A73G A248N A263G A290- A291- T489C A493G C522- A523- A750G A1438G A2706G T3552A A4715G A4769G C7028T C7196A T7334C G8584A A8701G A8860G T9540C A9545G T10031C A10398G C10400T T10873C G11719A G11914A C12705T A13263G T14318C C14766T T14783C G15043A G15301A A15326G A15487T C16223T T16298C T16325C C16327T MF588840(Canada-ancient-BTK45) Duggan Haplogroup A2 12-OCT-2017 C64T A73G T146C A153G T195C A235G A263G 309.1C 315.1C C522- A523- A663G A750G A1438G G1719A A1736G A2706G T4248C A4769G A4824G C7028T G8027A C8794T A8860G G11719A G12007A C12705T C14766T A15326G T16086C C16111T C16223T C16290T G16319A T16362C MF588841(Canada-ancient-BTK-46) Duggan Haplogroup D1 12-OCT-2017 A73G A263G C285T 315.1C T489C 745.1T A750G A1438G C2092T A2706G G3010A A4769G C4883T C5178A C7028T C7747T T8022C C8414T A8701G A8860G T9540C A10398G C10400T T10873C G11719A A11959G C12705T C14668T C14766T T14783C G15043A G15301A A15326G C15760T C16223T T16325C T16342C T16362C MF588846(Canada-ancient-BTK53) Duggan Haplogroup C4c1 12-OCT-2017 A73G G143A A263G 309.1C 315.1C T489C A750G T1243C A1438G 2232.1A A2706G T3552A A4715G A4769G G6026A C7028T C7043T T7064C C7196A G8584A A8701G A8860G T9540C A9545G A10398G C10400T T10873C G11719A G11914A G11969A C12705T A13263G T14318C C14433T C14766T T14783C G15043A G15148A T15204C G15301A A15326G A15487T C16223T T16298C C16327T T16519C MF588847(Canada-ancient-BTK54) Duggan Haplogroup D1 12-OCT-2017 A73G T213C A240G A263G 315.1C T489C A750G A1438G C2092T A2706G G3010A A4769G C4883T C5178A C6395T C7028T C7747T C8414T A8701G A8860G T9540C A10398G C10400T T10873C G11719A C12705T G14249A C14668T C14766T T14783C G15043A G15301A A15326G C16223T T16325C T16362C MF588850(Canada-ancient-BTK62) Duggan Haplogroup X2a1b 12-OCT-2017 A73G G143A A153G T195C A200G A263G 309.1C 315.1C A750G A1438G G1719A A2706G T3552C A4769G T6221C C6371T C7028T A8422G A8860G A8913G G11719A C11932T A12397G C12705T A13966G T14470C T14502C C14766T T15001C A15326G T16093C A16183- T16189C 16193.1C G16213A C16223T C16278T T16519C MF588851(Canada-ancient- BTK63) Duggan Haplogroup X2a1b 12-OCT-2017 A73G G143A A153G T195C A200G A263G 309.1C 315.1C A750G A1438G G1719A A2706G T3552C A4769G T6221C C6371T C7028T A8422G A8860G A8913G G11719A C11932T A12397G C12705T A13966G T14470C T14502C C14766T T15001C A15326G T16093C A16183- T16189C 16193.1C G16213A C16223T C16278T T16519C MF588857(Canada-ancient-BTK75) Duggan Haplogroup D2a1 12-OCT-2017 A73G T152C A263G 315.1C T489C C525T A750G A1438G A2706G G3010A G3316A A4769G C4883T C5178A C7028T A7424G C7493T C8414T A8701G C8703T A8860G C9536T T9540C A9667G A10398G C10400T T10873C G11176A C11215T G11719A A11959G C12705T C14668T C14766T T14783C G15043A G15301A A15326G T16092C G16129A C16223T T16362C MF588858(Canada-ancient-BTK76) Duggan Haplogroup C1b 12-OCT-2017 A73G A259G A263G A290- A291- 309.1C 315.1C T489C A493G C522- A523- A750G A1438G A2706G T3552A A4225G A4769G T5981C C7028T C7196A G8584A A8701G A8860G G9055A T9540C A9545G C10094T A10398G C10400T T10873C G11719A G11914A C12705T A13263G T14318C C14766T T14783C G15043A G15301A A15326G A15487T T16126C C16223T T16298C T16325C C16327T T16519C MF588860(Canada-ancient-BTK80) Duggan Haplogroup C4c1b 12-OCT-2017 A73G A263G 309.1C 315.1C T489C G513A A750G G1007A T1243C A1438G 2232.1A A2706G T3552A A4715G A4769G G6026A C7028T C7196A G8584A A8701G A8860G T9540C A9545G A10398G C10400T T10873C G11719A G11914A G11969A C12705T A13263G T14318C C14433T C14766T T14783C G15043A G15148A T15204C G15301A A15326G A15487T T16189C C16223T T16298C C16327T T16519C MF588862(Canada-ancient-BTK84) Duggan Haplogroup A2 12-OCT-2017 A73G T146C A153G A235G A263G 309.1C 315.1C C522- A523- A663G A750G A1438G A1736G A2706G C3330T T4248C A4769G A4824G C7028T C7633T G8027A C8794T A8860G G11719A G12007A C12705T C14766T A15326G C16111T C16192T C16223T C16290T G16319A T16362C MF588863(Canada-ancient-BTK88) Duggan Haplogroup D1 12-OCT-2017 A73G A263G C285T 315.1C T489C A750G A1438G C2092T A2706G G3010A A4769G C4883T C5178A C7028T C7747T T8022C C8414T A8701G A8860G T9540C A10398G C10400T T10873C G11719A A11959G C12705T C14668T C14766T T14783C G15043A G15301A A15326G C15760T C16223T T16325C T16362C