Continuing with my analysis of raw data files that have been 'fixed' for no-calls using SNP information from matching RSIDs found in 23andme and AncestryDNA. I uploaded the fixed files to gedmatch. My original kit from my 23andme was already in place. I used the Tier 1 utility, "Matching Segment Search." I used a minimum segment size of 5 cm without graphic. I downloaded the matching list of segments into an Excel Spreadsheet. I used the segment matches as I feel I get better information than the "one-to-many." Here are my results: 1925 gedmatch_segment_matches_M080859 (original 23andme kit with a 2.2 % error rate) 1741 gedmatch_segment_matches_M306764 (fixed 23andme kit with a 1.5 % error rate- about a 10% reduction in segment matches) 1263 gedmatch_segment_matches_A146269 (fixed Ancestry kit with a 1.0% error rate - I haven't uploaded my original AncestryDNA file) I do have issues with a lot of pileups on chromosome 15: Number of Segment Matches on Chromosome 15 - large number of pileups Original 23andme: 603 Fixed 23andme: 482 Fixed Ancestry: 197 Compared to number of Segment Matches on Chromosome 6: Original 23andme: 75 Fixed 23andme: 82 Fixed Ancestry: 84 It is an interesting situation. I expected fewer matches on my fixed kit, but I did not expect so much less on my ancestry kit. Any ideas why? I am going to dig deeper into the data. David -----Original Message----- From: David Schroeder [mailto:dschroed991@sbcglobal.net] Sent: Monday, December 14, 2015 10:48 PM To: 'genealogy-dna@rootsweb.com' Subject: RE: [DNA] My Raw Data Files - Comparison 23andme vs AncestryDNA I was able to 'fix' the no-calls for matching RSIDs on both Ancestry and 23andme when one, or the other, was not a no-call. I fixed 6,632 on 23andme and 6,708 on Ancestry. Interestingly enough, there were 3,833 that were left as no-calls on both 23andme and AncestryDNA for the same RSIDs. I am wondering if these are the result of particularly difficult locations to test, or perhaps the SNP is rare in my genome? The tests were over two years apart. I uploaded both fixed raw data files to gedmatch to see how it may affect my 'one-to-many' matches. (Will have to wait on the processing). I ran the Gedmatch File Diagnostic Utility, and the fixed files had significantly reduced my error rates. It seems that most of my errors are in the X, Y or MT Chromosomes. David