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    1. Re: [DNA] Genetic structure in Newfoundland and Labrador
    2. Paul Conroy via
    3. Murray, Fascinating! I've listened to YouTube videos of people sporting a "Newfie" accent, and they sound very similar to Irish accents to me. Cheers, Paul On Wednesday, December 23, 2015, Murray Bell <murraybel@msn.com> wrote: > I remember seeing a show on Canadian TV many years ago (probably 30) where > they went to a remote fishing village in Newfoundland and interviewed a > chap whose ancestors came from St. Mullins in County Carlow Ireland. They > also talked to residents of St. Mullins. The accent was the same & the > expressions were the same even though many generations had passed since > people from St. Mullins had immigrated to this remote Newfoundland fishing > village. This always stuck in my mind as I have been to St. Mullins and my > wife's grandparents are buried there. > > murray > > On Dec 19, 2015, at 6:19 AM, Paul Conroy via wrote: > > > Fascinating! The Irish population in Newfoundland is sourced from only a > > couple of specific areas: > > 1. Waterford, Wexford and Kilkenny in the Irish South East, mostly > > 2. Cork in the Irish South, to a lesser extent > > > > Both my parents show some Newfoundland relatives from SE Ireland. At one > > time many of these Irish people spoke Irish Gaelic (Gaeilge). In fact the > > last speaker of the Leinster dialect of Irish Gaelic, died in St John's > > some years ago. The dialect had died out in Ireland decades before that. > > > > Cheers, > > Paul > > > > On Thursday, December 17, 2015, Ann Turner via < > genealogy-dna@rootsweb.com <javascript:;>> > > wrote: > > > >> Genetic structure is detectable based on religious background in this > study > >> of Newfoundland and Labrador. That could be a consequence of marrying > >> someone with the same religion, even though the general geographic > >> background might not be that different. > >> > >> http://www.nature.com/ejhg/journal/vaop/ncurrent/full/ejhg2015256a.html > >> > >> Genetic structure of the Newfoundland and Labrador population: founder > >> effects modulate variability. > >> > >> Zhai G(1), Zhou J(2), Woods MO(1), Green JS(1), Parfrey P(2), Rahman > P(2), > >> Green RC(1). > >> > >> Author information: (1)Discipline of Genetics, Faculty of Medicine, > >> Memorial University of Newfoundland, St John's, Newfoundland and > Labrador, > >> Canada. (2)Discipline of Medicine, Faculty of Medicine, Memorial > >> University, St John's, Newfoundland and Labrador, Canada. > >> > >> The population of the province of Newfoundland and Labrador (NL) has > been a > >> resource for genetic studies because of its historical isolation and > >> increased prevalence of several monogenic disorders. Controversy remains > >> regarding the genetic substructure and the extent of genetic > homogeneity, > >> which have implications for disease gene mapping. Population > substructure > >> has been reported from other isolated populations such as Iceland, > Finland > >> and Sardinia. We undertook this study to further our understanding of > the > >> genetic architecture of the NL population. We enrolled 494 individuals > >> randomly selected from NL. Genome-wide SNP data were analyzed together > with > >> that from 14 other populations including HapMap3, Ireland, Britain and > >> Native American samples from the Human Genome Diversity Project. Using > >> multidimensional scaling and admixture analysis, we observed that the > >> genetic structure of the NL population resembles that of the British > >> population but can be divided into three clusters that correspond to > >> religious/ethnic origins: Protestant English, Roman Catholic Irish and > >> North American aboriginals. We observed reduced heterozygosity and an > >> increased inbreeding coefficient (mean=0.005), which corresponds to that > >> expected in the offspring of third-cousin marriages. We also found that > the > >> NL population has a significantly higher number of runs of homozygosity > >> (ROH) and longer lengths of ROH segments. These results are consistent > with > >> our understanding of the population history and indicate that the NL > >> population may be ideal for identifying recessive variants for complex > >> diseases that affect populations of European origin.European Journal of > >> Human Genetics advance online publication, 16 December 2015; > >> doi:10.1038/ejhg.2015.256. > >> > >> ------------------------------- > >> To unsubscribe from the list, please send an email to > >> GENEALOGY-DNA-request@rootsweb.com <javascript:;> <javascript:;> with > the word > >> 'unsubscribe' without the quotes in the subject and the body of the > message > >> > > > > ------------------------------- > > To unsubscribe from the list, please send an email to > GENEALOGY-DNA-request@rootsweb.com <javascript:;> with the word > 'unsubscribe' without the quotes in the subject and the body of the message > > > >

    12/24/2015 06:51:51