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    1. Re: [DNA] Genetic structure in Newfoundland and Labrador
    2. Ann Knight via
    3. Regarding accents - from an Australian ear, and as I have also lived in the United States - the US accent as a whole has always struck me as having Irish origins - and since there was such a huge influx of Irish to the US I would not be at all surprised about that. That's my 2 cents worth. Merry Christmas everyone. Ann On Fri, Dec 25, 2015 at 5:51 AM, Paul Conroy via <genealogy-dna@rootsweb.com > wrote: > Murray, > > Fascinating! > > I've listened to YouTube videos of people sporting a "Newfie" accent, and > they sound very similar to Irish accents to me. > > Cheers, > Paul > > On Wednesday, December 23, 2015, Murray Bell <murraybel@msn.com> wrote: > > > I remember seeing a show on Canadian TV many years ago (probably 30) > where > > they went to a remote fishing village in Newfoundland and interviewed a > > chap whose ancestors came from St. Mullins in County Carlow Ireland. They > > also talked to residents of St. Mullins. The accent was the same & the > > expressions were the same even though many generations had passed since > > people from St. Mullins had immigrated to this remote Newfoundland > fishing > > village. This always stuck in my mind as I have been to St. Mullins and > my > > wife's grandparents are buried there. > > > > murray > > > > On Dec 19, 2015, at 6:19 AM, Paul Conroy via wrote: > > > > > Fascinating! The Irish population in Newfoundland is sourced from only > a > > > couple of specific areas: > > > 1. Waterford, Wexford and Kilkenny in the Irish South East, mostly > > > 2. Cork in the Irish South, to a lesser extent > > > > > > Both my parents show some Newfoundland relatives from SE Ireland. At > one > > > time many of these Irish people spoke Irish Gaelic (Gaeilge). In fact > the > > > last speaker of the Leinster dialect of Irish Gaelic, died in St John's > > > some years ago. The dialect had died out in Ireland decades before > that. > > > > > > Cheers, > > > Paul > > > > > > On Thursday, December 17, 2015, Ann Turner via < > > genealogy-dna@rootsweb.com <javascript:;>> > > > wrote: > > > > > >> Genetic structure is detectable based on religious background in this > > study > > >> of Newfoundland and Labrador. That could be a consequence of marrying > > >> someone with the same religion, even though the general geographic > > >> background might not be that different. > > >> > > >> > http://www.nature.com/ejhg/journal/vaop/ncurrent/full/ejhg2015256a.html > > >> > > >> Genetic structure of the Newfoundland and Labrador population: founder > > >> effects modulate variability. > > >> > > >> Zhai G(1), Zhou J(2), Woods MO(1), Green JS(1), Parfrey P(2), Rahman > > P(2), > > >> Green RC(1). > > >> > > >> Author information: (1)Discipline of Genetics, Faculty of Medicine, > > >> Memorial University of Newfoundland, St John's, Newfoundland and > > Labrador, > > >> Canada. (2)Discipline of Medicine, Faculty of Medicine, Memorial > > >> University, St John's, Newfoundland and Labrador, Canada. > > >> > > >> The population of the province of Newfoundland and Labrador (NL) has > > been a > > >> resource for genetic studies because of its historical isolation and > > >> increased prevalence of several monogenic disorders. Controversy > remains > > >> regarding the genetic substructure and the extent of genetic > > homogeneity, > > >> which have implications for disease gene mapping. Population > > substructure > > >> has been reported from other isolated populations such as Iceland, > > Finland > > >> and Sardinia. We undertook this study to further our understanding of > > the > > >> genetic architecture of the NL population. We enrolled 494 individuals > > >> randomly selected from NL. Genome-wide SNP data were analyzed together > > with > > >> that from 14 other populations including HapMap3, Ireland, Britain and > > >> Native American samples from the Human Genome Diversity Project. Using > > >> multidimensional scaling and admixture analysis, we observed that the > > >> genetic structure of the NL population resembles that of the British > > >> population but can be divided into three clusters that correspond to > > >> religious/ethnic origins: Protestant English, Roman Catholic Irish and > > >> North American aboriginals. We observed reduced heterozygosity and an > > >> increased inbreeding coefficient (mean=0.005), which corresponds to > that > > >> expected in the offspring of third-cousin marriages. We also found > that > > the > > >> NL population has a significantly higher number of runs of > homozygosity > > >> (ROH) and longer lengths of ROH segments. These results are consistent > > with > > >> our understanding of the population history and indicate that the NL > > >> population may be ideal for identifying recessive variants for complex > > >> diseases that affect populations of European origin.European Journal > of > > >> Human Genetics advance online publication, 16 December 2015; > > >> doi:10.1038/ejhg.2015.256. > > >> > > >> ------------------------------- > > >> To unsubscribe from the list, please send an email to > > >> GENEALOGY-DNA-request@rootsweb.com <javascript:;> <javascript:;> with > > the word > > >> 'unsubscribe' without the quotes in the subject and the body of the > > message > > >> > > > > > > ------------------------------- > > > To unsubscribe from the list, please send an email to > > GENEALOGY-DNA-request@rootsweb.com <javascript:;> with the word > > 'unsubscribe' without the quotes in the subject and the body of the > message > > > > > > > > > ------------------------------- > To unsubscribe from the list, please send an email to > GENEALOGY-DNA-request@rootsweb.com with the word 'unsubscribe' without > the quotes in the subject and the body of the message >

    12/25/2015 12:52:21