Ian, this was just awesome to see!  So many mutations are familiar---and even though I know the Denisovans are ancient cousins but not ancestors, it is a thrill to see the connection.   More importantly, this gives me a chance to publicly thank you yet again for your eternal diligence in seeking out, checking and posting mtdna sequences from studies as they come out.  I have discovered that adding the relevant sequences from research studies to my mtdna match group data charts does wonders for clarifying connections, evaluating the value and behavior of various mutations and assessing valid times to common ancestors...in other words, to piece together the amazing untold historical tale lurking in the mtdna.  Without your work, doing this enlightening analysis would be difficult, if not impossible.  Words are inadequate for expressing the depth of my appreciation! DNA Detective and Denisovan-loving Dame Debra KatzmtDNA L2a1, HV1, U6a7, W3a, H1a, K1a1 From: "genealogy-dna-request@rootsweb.com" <genealogy-dna-request@rootsweb.com> To: genealogy-dna@rootsweb.com Sent: Tuesday, November 24, 2015 10:44 AM Subject: GENEALOGY-DNA Digest, Vol 10, Issue 641 Message: 1 Date: Tue, 24 Nov 2015 10:39:25 +0000 From: Ian Logan <ianlogan22@btinternet.com> Subject: [DNA]  Denisovan8 mtDNA sequence now on GenBank (21-NOV-2015) To: genealogy-dna@rootsweb.com Message-ID: <56543E5D.1020309@btinternet.com> Content-Type: text/plain; charset=utf-8; format=flowed List---Readers might be interested to see the mitochondrial details and abstract that accompany this paper: "Nuclear and mitochondrial DNA sequences from two Denisovan individuals" Sawyer,S., Renaud,G., Viola,B., Prufer,K., Kelso,J. and Paabo,S. A free download on: http://www.pnas.org/content/early/2015/11/11/1519905112.full.pdf The date of divergence of the Denisovan line from the modern human line would appear to be around 900-1,000 kya. Ian ----------------------------- Abstract: Denisovans, a sister group of Neandertals, have been described on the basis of a nuclear genome sequence from a finger phalanx (Denisova 3) found in Denisova Cave in the Altai Mountains. The only other Denisovan specimen described to date is a molar (Denisova 4) found at the same site. This tooth carries a mtDNA sequence similar to that of Denisova 3. Here we present nuclear DNA sequences from Denisova 4 and a morphological description, as well as mitochondrial and nuclear DNA sequence data, from another molar (Denisova 8) found in Denisova Cave in 2010. This new molar is similar to Denisova 4 in being very large and lacking traits typical of Neandertals and modern humans. Nuclear DNA sequences from the two molars form a clade with Denisova 3. The mtDNA of Denisova 8 is more diverged and has accumulated fewer substitutions than the mtDNAs of the other two specimens, suggesting Denisovans were present in the region over an extended period. The nuclear DNA sequence diversity among the three Denisovans is comparable to that among six Neandertals, but lower than that among present-day humans. ------------ KT780370 Denisovan8 21-NOV-2015  (371 CRS mutations) End of GENEALOGY-DNA Digest, Vol 10, Issue 641 **********************************************