I had not heard or thought about this concept properly, before I heard it from Thomas in a separate email about a week ago. I guess with the right tools it should enable cross-matches onto the X-Chromosome to be ruled out, but I start to get out of my depth here. Everything, long term, is going WGS - regulation permitting. I guess we would still only want the Y-DNA data out of that? At least with WGS you know there is nowhere else left to go in future! Brian -----Original Message----- From: genealogy-dna-bounces@rootsweb.com [mailto:genealogy-dna-bounces@rootsweb.com] On Behalf Of Thomas Krahn via Sent: 06 January 2016 00:07 To: genealogy-dna@rootsweb.com Subject: Re: [DNA] Full Genomes Corporation Tests Atanas The largest cost factor for Y chromosome tests is not the sequencing, but the enrichment procedure. With enrichment the price will never drop far below $400, so you might as well sequence with sufficient coverage. On the long run there is no future for Big Y and FGCs Y tests since the WGS tests keep dropping in the price, but Y tests don't. Thomas

As I know nothing about WGS I'd like to know more, especially regarding why "regulation permitting" it; and why "enrichment procedure" costs will not go down. Thanks Daryl On Jan 5, 2016 4:35 PM, "Brian Swann via" <genealogy-dna@rootsweb.com> wrote: > I had not heard or thought about this concept properly, before I heard it > from Thomas in a separate email about a week ago. > > I guess with the right tools it should enable cross-matches onto the > X-Chromosome to be ruled out, but I start to get out of my depth here. > > Everything, long term, is going WGS - regulation permitting. I guess we > would still only want the Y-DNA data out of that? > > At least with WGS you know there is nowhere else left to go in future! > > Brian > > -----Original Message----- > From: genealogy-dna-bounces@rootsweb.com > [mailto:genealogy-dna-bounces@rootsweb.com] On Behalf Of Thomas Krahn via > Sent: 06 January 2016 00:07 > To: genealogy-dna@rootsweb.com > Subject: Re: [DNA] Full Genomes Corporation Tests > > Atanas > > The largest cost factor for Y chromosome tests is not the sequencing, but > the enrichment procedure. With enrichment the price will never drop far > below $400, so you might as well sequence with sufficient coverage. > > On the long run there is no future for Big Y and FGCs Y tests since the WGS > tests keep dropping in the price, but Y tests don't. > > Thomas > > > ------------------------------- > To unsubscribe from the list, please send an email to > GENEALOGY-DNA-request@rootsweb.com with the word 'unsubscribe' without > the quotes in the subject and the body of the message >