I have a $75 Big Y coupon to the first person to ask .......
Thanks Lorna - your reply is excellent. I am away from my PC, and couldn't research an answer. Jim - www.segmentology.org > On Dec 22, 2015, at 5:01 PM, LornaMoa <lornamoa@gmail.com> wrote: > > David, > Haven't seen a reply go past so although I'm not Jim. > > Log in to GEDMatch > Click on the _*EDIT or DELETE your DNA resource profiles. > *_link below your list of kits > Select the one you want to remove from the public matching system and click Edit > > There's an option on that page where kits can be marked as Public, Private or Research > > Public / Private / Research: > (Research kits can be used with any GEDmatch utility, but they will not be shown in comparison results for other kits. We do NOT encourage the use of the 'Research' option with normal kit uploads, since it is not consistent with the free exchange of genealogy information.) > Public > Private > Research > > Very useful to mark what are essentially the same kit as Research, leaving just one of them pubic, > eg if you've uploaded your kits from all 3 companies, or as you've been doing, manipulating the no calls etc, the rest are all still available to you as Research kits. > > Lorna Henderson > http://LornaHen.com > >> On 23/12/15 02:28, David Hamill via wrote: >> Jim, could you share some details about how to go about uploading and notifying GEDmatch about research kits? I have some plans along these lines and am glad they have a way of handling them that won’t cause confusion for others. >> >> Thanks >> David >> >>> On Dec 22, 2015, at 3:00 AM, genealogy-dna-request@rootsweb.com wrote: >>> >>> No trouble. GEDmatch has a provision for research kits - it's important to notify them, so those kits don't gum up the works. The final kit can then be used for comparisons. The GEDmatch Admins have found, and removed, a few bogus kits from time to time. >>> >>> Jim - www.segmentology.org >> >> ------------------------------- >> To unsubscribe from the list, please send an email to GENEALOGY-DNA-request@rootsweb.com with the word 'unsubscribe' without the quotes in the subject and the body of the message >
The irritating part is that the immigrant couple is not identified. What possible good could this be to anyone without that information? Roberta Estes -----Original Message----- From: genealogy-dna-bounces@rootsweb.com [mailto:genealogy-dna-bounces@rootsweb.com] On Behalf Of steven perkins via Sent: Tuesday, December 22, 2015 7:41 PM To: genealogy-dna Subject: [DNA] Combined Genetic and Genealogic Studies Uncover a Large BAP1 Cancer Syndrome Kindred Tracing Back Nine Generations to a Common Ancestor from the 1700s http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1005633 Combined Genetic and Genealogic Studies Uncover a Large BAP1 Cancer Syndrome Kindred Tracing Back Nine Generations to a Common Ancestor from the 1700s Abstract: We recently discovered an inherited cancer syndrome caused by BRCA1-Associated Protein 1 (BAP1) germline mutations, with high incidence of mesothelioma, uveal melanoma and other cancers and very high penetrance by age 55. To identify families with the BAP1 cancer syndrome, we screened patients with family histories of multiple mesotheliomas and melanomas and/or multiple cancers. We identified four families that shared an identical BAP1mutation: they lived across the US and did not appear to be related. By combining family histories, molecular genetics, and genealogical approaches, we uncovered a BAP1 cancer syndrome kindred of ~80,000 descendants with a core of 106 individuals, whose members descend from a couple born in Germany in the early 1700s who immigrated to North America. Their descendants spread throughout the country with mutation carriers affected by multiple malignancies. Our data show that, once a proband is identified, extended analyses of these kindreds, using genomic and genealogical studies to identify the most recent common ancestor, allow investigators to uncover additional branches of the family that may carry BAP1mutations. Using this knowledge, we have identified new branches of this family carrying BAP1 mutations. We have also implemented early-detection strategies that help identify cancers at early-stage, when they can be cured (melanomas) or are more susceptible to therapy (MM and other malignancies). Author Summary Germline BAP1 mutations cause a cancer syndrome characterized by high incidence of mesothelioma (MM), uveal melanoma and other cancers, and by very high penetrance, as all individuals carrying BAP1 mutations developed at least one, and usually several, malignancies throughout their lives. Through screening MM patients with histories of multiple cancers, we found four supposedly unrelated patients that shared an identical germline BAP1 mutation. We investigated whether this BAP1 mutation occurred in a ‘hot-spot’ for “de novo” mutations or whether these four MM patients shared a common ancestor. Using molecular genomics analyses we found that they are related. By genealogic studies we traced their ancestor to a couple that emigrated from Germany to North America in the early 1700’s; we traced the subsequent migration of their descendants, who are now living in at least three different US States. Our findings demonstrate that BAP1 mutations are transmitted among subsequent generations over the course of centuries. This knowledge and methodology is being used to identify additional branches of the family carrying BAP1 mutations. Our study shows that the application of modern genomic analyses, coupled with “classical” family histories collected by th! e treating physician, and with genealogical searches, offer a powerful strategy to identify high-risk germline BAP1 mutation carriers that will benefit from genetic counseling and early detection cancer screening. -- Steven C. Perkins SCPerkins@gmail.com http://stevencperkins.com/ Indigenous Peoples' Rights http://intelligent-internet.info/law/ipr2.html Indigenous & Ethnic Minority Legal News http://iemlnews.blogspot.com/ Online Journal of Genetics and Genealogy http://jgg-online.blogspot.com/ S.C. Perkins' Genealogy Page http://stevencperkins.com/genealogy.html S.C. Perkins' Genealogy Blog http://scpgen.blogspot.com/ ------------------------------- To unsubscribe from the list, please send an email to GENEALOGY-DNA-request@rootsweb.com with the word 'unsubscribe' without the quotes in the subject and the body of the message
It's too bad they don't name these German immigrants. Maybe more of us could determine that we are affected -----Original Message----- From: steven perkins via <genealogy-dna@rootsweb.com> To: genealogy-dna <genealogy-dna@rootsweb.com> Sent: Tue, Dec 22, 2015 4:42 pm Subject: [DNA] Combined Genetic and Genealogic Studies Uncover a Large BAP1 Cancer Syndrome Kindred Tracing Back Nine Generations to a Common Ancestor from the 1700s http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1005633Combined Genetic and Genealogic Studies Uncover a Large BAP1 CancerSyndrome Kindred Tracing Back Nine Generations to a Common Ancestor fromthe 1700sAbstract:We recently discovered an inherited cancer syndrome caused byBRCA1-Associated Protein 1 (BAP1) germline mutations, with high incidenceof mesothelioma, uveal melanoma and other cancers and very high penetranceby age 55. To identify families with the BAP1 cancer syndrome, we screenedpatients with family histories of multiple mesotheliomas and melanomasand/or multiple cancers. We identified four families that shared anidentical BAP1mutation: they lived across the US and did not appear to berelated. By combining family histories, molecular genetics, andgenealogical approaches, we uncovered a BAP1 cancer syndrome kindred of~80,000 descendants with a core of 106 individuals, whose members descendfrom a couple born in Germany in the early 1700s who immigrated to NorthAmerica. Their descendants spread throughout the country with mutationcarriers affected by multiple malignancies. Our data show that, once aproband is identified, extended analyses of these kindreds, using genomicand genealogical studies to identify the most recent common ancestor, allowinvestigators to uncover additional branches of the family that may carryBAP1mutations. Using this knowledge, we have identified new branches ofthis family carrying BAP1 mutations. We have also implementedearly-detection strategies that help identify cancers at early-stage, whenthey can be cured (melanomas) or are more susceptible to therapy (MM andother malignancies).Author SummaryGermline BAP1 mutations cause a cancer syndrome characterized by highincidence of mesothelioma (MM), uveal melanoma and other cancers, and byvery high penetrance, as all individuals carrying BAP1 mutations developedat least one, and usually several, malignancies throughout their lives.Through screening MM patients with histories of multiple cancers, we foundfour supposedly unrelated patients that shared an identical germline BAP1mutation. We investigated whether this BAP1 mutation occurred in a‘hot-spot’ for “de novo” mutations or whether these four MM patients shareda common ancestor. Using molecular genomics analyses we found that they arerelated. By genealogic studies we traced their ancestor to a couple thatemigrated from Germany to North America in the early 1700’s; we traced thesubsequent migration of their descendants, who are now living in at leastthree different US States. Our findings demonstrate that BAP1 mutations aretransmitted among subsequent generations over the course of centuries. Thisknowledge and methodology is being used to identify additional branches ofthe family carrying BAP1 mutations. Our study shows that the application ofmodern genomic analyses, coupled with “classical” family historiescollected by the treating physician, and with genealogical searches, offera powerful strategy to identify high-risk germline BAP1 mutation carriersthat will benefit from genetic counseling and early detection cancerscreening.-- Steven C. Perkins SCPerkins@gmail.com http://stevencperkins.com/Indigenous Peoples' Rights http://intelligent-internet.info/law/ipr2.htmlIndigenous & Ethnic Minority Legal News http://iemlnews.blogspot.com/Online Journal of Genetics and Genealogy http://jgg-online.blogspot.com/S.C. Perkins' Genealogy Page http://stevencperkins.com/genealogy.htmlS.C. Perkins' Genealogy Blog http://scpgen.blogspot.com/ -------------------------------To unsubscribe from the list, please send an email to GENEALOGY-DNA-request@rootsweb.com with the word 'unsubscribe' without the quotes in the subject and the body of the message
http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1005633 Combined Genetic and Genealogic Studies Uncover a Large BAP1 Cancer Syndrome Kindred Tracing Back Nine Generations to a Common Ancestor from the 1700s Abstract: We recently discovered an inherited cancer syndrome caused by BRCA1-Associated Protein 1 (BAP1) germline mutations, with high incidence of mesothelioma, uveal melanoma and other cancers and very high penetrance by age 55. To identify families with the BAP1 cancer syndrome, we screened patients with family histories of multiple mesotheliomas and melanomas and/or multiple cancers. We identified four families that shared an identical BAP1mutation: they lived across the US and did not appear to be related. By combining family histories, molecular genetics, and genealogical approaches, we uncovered a BAP1 cancer syndrome kindred of ~80,000 descendants with a core of 106 individuals, whose members descend from a couple born in Germany in the early 1700s who immigrated to North America. Their descendants spread throughout the country with mutation carriers affected by multiple malignancies. Our data show that, once a proband is identified, extended analyses of these kindreds, using genomic and genealogical studies to identify the most recent common ancestor, allow investigators to uncover additional branches of the family that may carry BAP1mutations. Using this knowledge, we have identified new branches of this family carrying BAP1 mutations. We have also implemented early-detection strategies that help identify cancers at early-stage, when they can be cured (melanomas) or are more susceptible to therapy (MM and other malignancies). Author Summary Germline BAP1 mutations cause a cancer syndrome characterized by high incidence of mesothelioma (MM), uveal melanoma and other cancers, and by very high penetrance, as all individuals carrying BAP1 mutations developed at least one, and usually several, malignancies throughout their lives. Through screening MM patients with histories of multiple cancers, we found four supposedly unrelated patients that shared an identical germline BAP1 mutation. We investigated whether this BAP1 mutation occurred in a ‘hot-spot’ for “de novo” mutations or whether these four MM patients shared a common ancestor. Using molecular genomics analyses we found that they are related. By genealogic studies we traced their ancestor to a couple that emigrated from Germany to North America in the early 1700’s; we traced the subsequent migration of their descendants, who are now living in at least three different US States. Our findings demonstrate that BAP1 mutations are transmitted among subsequent generations over the course of centuries. This knowledge and methodology is being used to identify additional branches of the family carrying BAP1 mutations. Our study shows that the application of modern genomic analyses, coupled with “classical” family histories collected by the treating physician, and with genealogical searches, offer a powerful strategy to identify high-risk germline BAP1 mutation carriers that will benefit from genetic counseling and early detection cancer screening. -- Steven C. Perkins SCPerkins@gmail.com http://stevencperkins.com/ Indigenous Peoples' Rights http://intelligent-internet.info/law/ipr2.html Indigenous & Ethnic Minority Legal News http://iemlnews.blogspot.com/ Online Journal of Genetics and Genealogy http://jgg-online.blogspot.com/ S.C. Perkins' Genealogy Page http://stevencperkins.com/genealogy.html S.C. Perkins' Genealogy Blog http://scpgen.blogspot.com/
- We had three ancient Northern J1 results: 1- Sarmatian J1, Beslan, North Ossetia (2/3 C. A.D.) Gennady Afanasiev. Khazar Confederates in the Don basin. Pure research methods and the paradigm of modern archeology. M. 2015. S.146-153. (Afanasiev:2015). 2 - Karelian J1 Eastern Hunther-Gatherer from Russia, Yuzhnyy Oleni Ostrov [I0211/UzOO 40], M, 5500-5000 BC. (Mathieson:2015). 3 - Satsurblia cave J1, Georgia, F4306+, 13000 YBP (Jones:2015). - We have discovered and confirmed our own 14000 years old branch SNP FGC6064 comparing my results FTDNA 73612-YFull YF01554 (I have 188 new SNPs to be tested FGC5987 to FGC6175) with the Big Y results from Kitching, England, 381875-YF03848. - FTDNA is still boycotting our J1-M365 SNP. M365 was discovered in 2004, the M365 SNP has been in ISOGG's list since 2006 and M365 is also present at the last Y Chromosome Consortium (YCC). I had M365 as my terminal SNP in FTDNA in 2007. People from my J-M365 Project paid and tested positive for M365. We have M365+ in our J1 report. We have several people now listed as J1-M267 and not J1-M365 as our terminal SNP. We have recurrent SNPs in the case of almost all SNPs and M365 is quite old, so it was found and listed in other branches, like R-M365 in FTDNA's haplotree. Our J1-M365 was discovered in 2004 and is extremely valid, useful and important. So we are only asking to our terminal J1-M365 SNP to be where it was in FTDNA haplotree in 2007 because we paid, tested positive and that's our J1 group. Please FTDNA, we need our J1-M365 downstream SNP of FGC6064 in the haplotree. - YFull tree, the best NGS public tree, now has J1-M365 as a node. Now we are waiting the analysis of another Portuguese Big Y BAM YF04781 results there. - Now it's obvious that J1 was born and emerged in the Northern Near Eastern regions around the Black Sea, Eastern Anatolia, the Caucasus, the Caspian Sea and Northern Iran where the ancient types of J1 and the basal branches were discovered and still can be found there nowadays. No research or article has ever investigated basal types and SNPs of J1 from the cradle areas. We depend on the private tests and the citizen scientists only. I need some Gilaki and Caspian or Northern Iranian J1 types matching our M365 cluster in terms of STR to be fully sequenced with NGS. I will pay and finance that research but I need the samples ! Let's wait 2016. A Ricardo Merry Christmas and Happy New Year !
Jim, could you share some details about how to go about uploading and notifying GEDmatch about research kits? I have some plans along these lines and am glad they have a way of handling them that won’t cause confusion for others. Thanks David > On Dec 22, 2015, at 3:00 AM, genealogy-dna-request@rootsweb.com wrote: > > No trouble. GEDmatch has a provision for research kits - it's important to notify them, so those kits don't gum up the works. The final kit can then be used for comparisons. The GEDmatch Admins have found, and removed, a few bogus kits from time to time. > > Jim - www.segmentology.org
Hi Ricardo, Merry Christmas & Happy New Year! Write to Mr. Greenspan , tell him your story and the J1-M365 results of testing and findings. I'm sure FTDNA will add your branch onto "Haplotree", You may have already done that though? Al On Tue, Dec 22, 2015 at 4:30 AM, Ricardo Costa de Oliveira via < genealogy-dna@rootsweb.com> wrote: > - We had three ancient Northern J1 results: > > 1- Sarmatian J1, Beslan, North Ossetia (2/3 C. A.D.) Gennady Afanasiev. > Khazar Confederates in the Don basin. Pure research methods and the > paradigm of modern archeology. M. 2015. S.146-153. (Afanasiev:2015). > > 2 - Karelian J1 Eastern Hunther-Gatherer from Russia, Yuzhnyy Oleni > Ostrov [I0211/UzOO 40], M, 5500-5000 BC. (Mathieson:2015). > > 3 - Satsurblia cave J1, Georgia, F4306+, 13000 YBP (Jones:2015). > > - We have discovered and confirmed our own 14000 years old branch SNP > FGC6064 comparing my results FTDNA 73612-YFull YF01554 (I have 188 new > SNPs to be tested FGC5987 to FGC6175) with the Big Y results from > Kitching, England, 381875-YF03848. > > - FTDNA is still boycotting our J1-M365 SNP. M365 was discovered in > 2004, the M365 SNP has been in ISOGG's list since 2006 and M365 is also > present at the last Y Chromosome Consortium (YCC). I had M365 as my > terminal SNP in FTDNA in 2007. People from my J-M365 Project paid and > tested positive for M365. We have M365+ in our J1 report. We have > several people now listed as J1-M267 and not J1-M365 as our terminal > SNP. We have recurrent SNPs in the case of almost all SNPs and M365 is > quite old, so it was found and listed in other branches, like R-M365 in > FTDNA's haplotree. Our J1-M365 was discovered in 2004 and is extremely > valid, useful and important. So we are only asking to our terminal > J1-M365 SNP to be where it was in FTDNA haplotree in 2007 because we > paid, tested positive and that's our J1 group. Please FTDNA, we need > our J1-M365 downstream SNP of FGC6064 in the haplotree. > > - YFull tree, the best NGS public tree, now has J1-M365 as a node. Now > we are waiting the analysis of another Portuguese Big Y BAM YF04781 > results there. > > - Now it's obvious that J1 was born and emerged in the Northern Near > Eastern regions around the Black Sea, Eastern Anatolia, the Caucasus, > the Caspian Sea and Northern Iran where the ancient types of J1 and the > basal branches were discovered and still can be found there nowadays. > No research or article has ever investigated basal types and SNPs of J1 > from the cradle areas. We depend on the private tests and the citizen > scientists only. I need some Gilaki and Caspian or Northern Iranian J1 > types matching our M365 cluster in terms of STR to be fully sequenced > with NGS. I will pay and finance that research but I need the samples ! > Let's wait 2016. > > A > > Ricardo > > Merry Christmas and Happy New Year ! > > ------------------------------- > To unsubscribe from the list, please send an email to > GENEALOGY-DNA-request@rootsweb.com with the word 'unsubscribe' without > the quotes in the subject and the body of the message >
I have good coupons for Big Y this week-- one for $100, one for $75 and one for $50. I'll send them directly to the first people who ask.
David: I used to have a combined kit at GEDMATCH (FTDNA + 23andMe + AncestryDNA) starting with a capital "C". I can no longer search or do comparisons with that number. I am very interested in whether your file will work. Regards, Steven On Mon, Dec 21, 2015 at 7:00 AM, Jim Bartlett via < genealogy-dna@rootsweb.com> wrote: > No trouble. GEDmatch has a provision for research kits - it's important to > notify them, so those kits don't gum up the works. The final kit can then > be used for comparisons. The GEDmatch Admins have found, and removed, a > few bogus kits from time to time. > > Jim - www.segmentology.org > > > On Dec 21, 2015, at 4:23 AM, Sam Sloan via <genealogy-dna@rootsweb.com> > wrote: > > > > If they catch you doing this, will you get into trouble? > > > > On Sun, Dec 20, 2015 at 7:29 PM, David Schroeder via < > > genealogy-dna@rootsweb.com> wrote: > > > >> Hello Dave, > >> > >> Most of this is going to have to wait until after the holidays. Here is > >> what > >> I am planning to do: > >> > >> 1). Create a hybrid raw data file from both 23andme and AncestryDNA > using > >> the full complement on RSIDs found on both and upload to gedmatch. (I > have > >> already created kits using my original raw data files, and kits with the > >> 'no-calls' fixed using information from both 23andme and AncestryDNA). > The > >> new raw data file will essentially be all the RSIDs on 23andme plus the > >> RSIDs on AncestryDNA that are not found on 23andme. > >> > >> 2). I plan to use the segment matching tool in gedmatch on all five kits > >> and > >> upload the information into a MySQL database. That way I can run > queries to > >> try to understand the situation, and hopefully understand the > differences. > >> There is a lot of information to work with: Start, Stop, and cM- as > well as > >> match name. > >> > >> David > > > ------------------------------- > To unsubscribe from the list, please send an email to > GENEALOGY-DNA-request@rootsweb.com with the word 'unsubscribe' without > the quotes in the subject and the body of the message > -- Steven C. Perkins SCPerkins@gmail.com http://stevencperkins.com/ Indigenous Peoples' Rights http://intelligent-internet.info/law/ipr2.html Indigenous & Ethnic Minority Legal News http://iemlnews.blogspot.com/ Online Journal of Genetics and Genealogy http://jgg-online.blogspot.com/ S.C. Perkins' Genealogy Page http://stevencperkins.com/genealogy.html S.C. Perkins' Genealogy Blog http://scpgen.blogspot.com/
No trouble. GEDmatch has a provision for research kits - it's important to notify them, so those kits don't gum up the works. The final kit can then be used for comparisons. The GEDmatch Admins have found, and removed, a few bogus kits from time to time. Jim - www.segmentology.org > On Dec 21, 2015, at 4:23 AM, Sam Sloan via <genealogy-dna@rootsweb.com> wrote: > > If they catch you doing this, will you get into trouble? > > On Sun, Dec 20, 2015 at 7:29 PM, David Schroeder via < > genealogy-dna@rootsweb.com> wrote: > >> Hello Dave, >> >> Most of this is going to have to wait until after the holidays. Here is >> what >> I am planning to do: >> >> 1). Create a hybrid raw data file from both 23andme and AncestryDNA using >> the full complement on RSIDs found on both and upload to gedmatch. (I have >> already created kits using my original raw data files, and kits with the >> 'no-calls' fixed using information from both 23andme and AncestryDNA). The >> new raw data file will essentially be all the RSIDs on 23andme plus the >> RSIDs on AncestryDNA that are not found on 23andme. >> >> 2). I plan to use the segment matching tool in gedmatch on all five kits >> and >> upload the information into a MySQL database. That way I can run queries to >> try to understand the situation, and hopefully understand the differences. >> There is a lot of information to work with: Start, Stop, and cM- as well as >> match name. >> >> David
Probably more related to family history and life style ... "social genes" --- memes ... :-) A union boss on one side ... A saloon operator on the other ... On Sat, Dec 19, 2015 at 1:45 PM, Paul Conroy via <genealogy-dna@rootsweb.com > wrote: > So being a blowhard is in the genes? > > On Saturday, December 19, 2015, G. Magoon via <genealogy-dna@rootsweb.com> > wrote: > > > > > > http://abcnews.go.com/Entertainment/wireStory/pbs-series-finds-bills-related-35802398 > > This is an article I just came across from the Associated Press, > associated > > with "Finding Your Roots". CeCe Moore is quoted. > > > > ------------------------------- > > To unsubscribe from the list, please send an email to > > GENEALOGY-DNA-request@rootsweb.com <javascript:;> with the word > > 'unsubscribe' without the quotes in the subject and the body of the > message > > > > ------------------------------- > To unsubscribe from the list, please send an email to > GENEALOGY-DNA-request@rootsweb.com with the word 'unsubscribe' without > the quotes in the subject and the body of the message >
If they catch you doing this, will you get into trouble? On Sun, Dec 20, 2015 at 7:29 PM, David Schroeder via < genealogy-dna@rootsweb.com> wrote: > Hello Dave, > > Most of this is going to have to wait until after the holidays. Here is > what > I am planning to do: > > 1). Create a hybrid raw data file from both 23andme and AncestryDNA using > the full complement on RSIDs found on both and upload to gedmatch. (I have > already created kits using my original raw data files, and kits with the > 'no-calls' fixed using information from both 23andme and AncestryDNA). The > new raw data file will essentially be all the RSIDs on 23andme plus the > RSIDs on AncestryDNA that are not found on 23andme. > > 2). I plan to use the segment matching tool in gedmatch on all five kits > and > upload the information into a MySQL database. That way I can run queries to > try to understand the situation, and hopefully understand the differences. > There is a lot of information to work with: Start, Stop, and cM- as well as > match name. > > David > > > > ------------------------------ > > Message: 4 > Date: Sun, 20 Dec 2015 07:59:33 -0500 > From: Dave Hamm <odoniv@earthlink.net> > Subject: Re: [DNA] My Raw Data Files - Comparison 23andme vs, > AncestryDNA > To: genealogy-dna@rootsweb.com > Message-ID: <5676A635.9030809@earthlink.net> > Content-Type: text/plain; charset=utf-8; format=flowed > > Hi David, > > I was wondering if we can identify by SNP count (by segment age from my > cousin calculator). > > RE: > > These matches are with people I am not related to. Form me, it is > chromosome 15 from positions 233,000 to 293,000 where I have several > hundred > matches. > > Can you give a couple of examples with start and end locations, along with > cMs and SNP counts for the segments(s)?? > > - Dave Hamm > > HAM DNA Project coordinator > > > > ------------------------------- > To unsubscribe from the list, please send an email to > GENEALOGY-DNA-request@rootsweb.com with the word 'unsubscribe' without > the quotes in the subject and the body of the message >
Hello Dave, Most of this is going to have to wait until after the holidays. Here is what I am planning to do: 1). Create a hybrid raw data file from both 23andme and AncestryDNA using the full complement on RSIDs found on both and upload to gedmatch. (I have already created kits using my original raw data files, and kits with the 'no-calls' fixed using information from both 23andme and AncestryDNA). The new raw data file will essentially be all the RSIDs on 23andme plus the RSIDs on AncestryDNA that are not found on 23andme. 2). I plan to use the segment matching tool in gedmatch on all five kits and upload the information into a MySQL database. That way I can run queries to try to understand the situation, and hopefully understand the differences. There is a lot of information to work with: Start, Stop, and cM- as well as match name. David ------------------------------ Message: 4 Date: Sun, 20 Dec 2015 07:59:33 -0500 From: Dave Hamm <odoniv@earthlink.net> Subject: Re: [DNA] My Raw Data Files - Comparison 23andme vs, AncestryDNA To: genealogy-dna@rootsweb.com Message-ID: <5676A635.9030809@earthlink.net> Content-Type: text/plain; charset=utf-8; format=flowed Hi David, I was wondering if we can identify by SNP count (by segment age from my cousin calculator). RE: > These matches are with people I am not related to. Form me, it is chromosome 15 from positions 233,000 to 293,000 where I have several hundred matches. Can you give a couple of examples with start and end locations, along with cMs and SNP counts for the segments(s)?? - Dave Hamm HAM DNA Project coordinator
Sam, is this relationship been proven via triangulation? Even then the third person (or even others if the TG is larger) needs to match so where into the same family tree branch. Has that manifested? Otherwise (and despite being a fascinating story) it's a questionable relationship to start with. Andreas > On 20 Dec 2015, at 02:28, Sam Sloan via <genealogy-dna@rootsweb.com> wrote: > > Amazing Discovery through Ancestry – My Black 6th Cousins > > Ancestry dot com has made a lot of changes lately. I hope they are for the > better but they require some getting used to. > > When I took a look at their new (I think) Ancestry DNA insights page, at > the top row of their DNA matches, I found the picture of a Black woman who, > it said, has a *Predicted relationship: Distant Cousins **with me. Possible > range: 5th - 8th cousins *Confidence: Moderate > > Naturally, I was surprised at this as I am lily white, Swedish and Irish > and there is no record of my family owning slaves. > > However, using the new tools available on Ancestry plus my own family tree > that I have been working on for the last twenty years, I was able to solve > this mystery in about fifteen minutes. > > My grandfather , my mothers father, was Wesley Jacobson (1877-1963). His > family on both sides settled Iowa in 1845 arriving from Kisa, Ostergotland, > Sweden . Using the Disbyt Database, a huge Swedish genealogical data base, > I was able to trace his ancestors back to Sven Bengtsson who had a death > date of 12 OCT 1729 in Ulrika, Ostergotland, Sweden but no birth date. > > You can see him here on my rootsweb family tree > > http://wc.rootsweb.ancestry.com/cgi-bin/igm.cgi?op=GET&db=samsloan&id=I6668 > > Ancestry had another family tree that showed who his father was. His father > was Per Hemmingsson, who was born 1630 in Kisa, Östergötlands Län, Sweden > > It appears that in about 1650 Per Hemmingsson, my 7th great-grandfather, > led a group of Swedes to establish a settlement in *Bandundu *in what is > now the Democratic Republic of the Congo > <https://en.wikipedia.org/wiki/Democratic_Republic_of_the_Congo>. > > https://en.wikipedia.org/wiki/Bandundu_%28city%29 > > They named the community they established Kisa, Bandundu, Congo, giving it > the same name as the name of their home town in Sweden. > > However, the settlement did not last long, as he died there. However, he > had a son who was born there by his Swedish wife Gunilla Birgersdottir. The > son was Sven Bengtsson (1650–1729) who was born in Kisa, Bandundu, Congo in > 1650 and died in Kisa,Östergötlands Län, Sweden 1729. He is my 6th > great-grandfather. > > After the death of Per Hemmingsson, it appears that the entire group went > back to Sweden. However, before leaving for Sweden, being a fair minded and > generous person, Per Hemmingsson contributed his own DNA to the local > population and, as a result, I have a sixth cousin born in deepest Darkest > Africa !!! > > Please note how early this date was. David Livingstone (1813-1873) was one > of the earliest European explorers of Africa and he was “found” by Stanley > in 1871. Henry Morton Stanley (1841-1904) is credited with being the first > European to explore the Congo River, yet, my ancestors were living on the > Congo River down in Central Africa in 1650 two hundred years before that > and not long after the *Mayflower* Pilgrims > <https://en.wikipedia.org/wiki/Pilgrims_%28Plymouth_Colony%29> landed on > Plymouth Rock. This is proven by the DNA test results. > > Indeed, nobody would even believe this incredible story but now we have the > proof unless somebody can figure out another way I could possibly have a 6th > cousin living on the Congo River in Africa today. > > Sam Sloan > > ------------------------------- > To unsubscribe from the list, please send an email to GENEALOGY-DNA-request@rootsweb.com with the word 'unsubscribe' without the quotes in the subject and the body of the message
Dear Patti, I believe that it is possible to sort issues out such as what you described using autosomal DNA analysis. However, you need to have enough people tested so that you can be reasonably certain about the conclusions that you draw from your analysis. You might want to review the analysis that I did at https://blog.23andme.com/ancestry/who-were-the-parents-of-jacob-youngman. This is similar to the type of analysis that you will need to do. In your case, the closest possible relationship between the great grandson of Robert Purtell and you is 2nd cousin once removed. Your uncle could be a 2nd cousin of great grandson of Robert Purtell. In the case of 2nd cousins you would expect about 220 cMs to be shared between the two people involved and for 2nd cousins once removed you would expect about 110 cMs to be shared between the two people involved. If you aren't seeing the total cMs shared between the people involved using the chromosome browser at 23andMe then this would suggest that the genealogical relationship is more distant. Testing more people from various lines of descent can help you better determine the probable genealogical relationship, particularly if the genealogical relationship is more distant than 3rd cousins. Sincerely, Tim Janzen -----Original Message----- From: genealogy-dna-bounces@rootsweb.com [mailto:genealogy-dna-bounces@rootsweb.com] On Behalf Of Patti Hacht via Sent: Saturday, December 19, 2015 7:11 PM To: genealogy-dna@rootsweb.com Subject: [DNA] Three brothers from 1800's and recent DNA matches. I have a question regarding three Irish brothers. For forty plus years I have been researching my Purtell line from near Kilcolman (Shanagolden area) of Co Limerick, Ireland. I discovered my 2nd gr-grandfather, John Purtell b cir 1816 probably in Kilcolman parish. In the Kilcolman Parish rcds, I find a Laurence Purtell who was the sponsor in several of John's children's baptisms. I have thought that Laurence might be John's brother as he was born abt 1810. Laurence emigrated to Binghamton, NY about 1849. About a year later, my John followed Laurence to Binghamton, NY. Within four years, my John had moved further west to Michigan. Then there was a Robert Purtell, said to be related somehow to my John. Robert was born abt 1808 (probably Kilcolman) and emigrated to LaSalette, Ontario, Canada in the 1840's. Members of Robert's family eventually made their way to Midland, Michigan. Enter DNA testing. My brother and my Uncle (who's mother was a Purtell) both DNA match the great grandson of Robert Purtell from LaSalette. (My sister and I do *not* match the LaSalette Purtell's.) And now my brother and "Purtell" uncle also match a descendant of Laurence's from Binghamton. My question is, is there a way (using our DNA matches) to figure out if Robert b 1808, Laurence b 1810 and John b 1816 might have really been brothers? Patti in Lakeville, MIchigan
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Doug, When is the closest to now terminal SNP that is found in the Donald clan? Are breaking into the genealogical time frame? Andreas > On 18 Dec 2015, at 00:39, McDonald@lists3.rootsweb.com wrote: > > We too in the large R1a Clan Donald BigY project have found people with much > larger than expected numbers of SNPs under YP274 (which happened about AD 1100). > HOWEVER, we have enough that the distribution is, within reasonable error, the > expected Poisson one. > > Doug McDonald > > -----Original Message----- > From: genealogy-dna-bounces@rootsweb.com [mailto:genealogy-dna-bounces@rootsweb.com] On Behalf Of Marleen Van Horne via > Sent: Wednesday, December 16, 2015 1:02 PM > To: Genealogy > Subject: [DNA] yDNA Terminal SNP Y10633 T+ > > Those of you who have been on the Genealogy-DNA list for awhile will > remember a couple of years ago when I commissioned a TMRCA Challenge on > three surnames that yDNA testing indicated had a common ancestor. The > three surnames were Group 20 in the Walker Project and Christensen and > Van Horne in the Van Horne Project. > > Earlier this year, a member of the Walker Group 20 did advanced yDNA > testing in which the SNP Y10633 T+ was identified as the terminal SNP. > Subsequently a Christensen and a Van Horne have been tested, they are > both positive for the SNP. > > The Walker family lived in Britain probably for several hundred years > before immigrating to North America. The Christensen immigrant ancestor > arrived in the US in 1905 from Denmark. The Van Horne immigrant > ancestor arrived in North America in 1663 from Denmark. > > I have not corresponded with Ken Nordtvedt, it is my understanding he > places the original male ancestor of these three families as living in > Norway about 2200 years ago. This also confirms and extends the > estimates from the TMRCA Challenge. > > It was noted in the Challenge report that a node of three individuals in > the Van Horne family had a higher than expected rate of mutation. It > was suggested these men were not members of the Van Horne family, and > that the conventional research was incorrect. The member of the Van > Horne family who did the SNP test was from this node. In fact, he was > the family member with the most mutations. > > Those of you who have high mutation nodes in your families should not > discount these men, without doing additional testing to confirm or > disprove the relationship. > > Now, can anyone tell me how we get this yDNA terminal SNP documented in > the yDNA Phylogenetic Tree. > > Marleen Van Horne > > ------------------------------- > To unsubscribe from the list, please send an email to GENEALOGY-DNA-request@rootsweb.com with the word 'unsubscribe' without the quotes in the subject and the body of the message > > > ------------------------------- > To unsubscribe from the list, please send an email to GENEALOGY-DNA-request@rootsweb.com with the word 'unsubscribe' without the quotes in the subject and the body of the message
I would say the crucial missing piece of information here is *how much* they match. After all I match people to whom I could not be related in the past three hundred years Your guys should match fairly clearly, whats the cm sizes involved? . -----Original Message----- From: Robert Paine via <genealogy-dna@rootsweb.com> To: Patti Hacht <duncaha@gmail.com>; genealogy-dna <genealogy-dna@rootsweb.com> Sent: Sat, Dec 19, 2015 8:08 pm Subject: Re: [DNA] Three brothers from 1800's and recent DNA matches. Patti Out of curiosity which testing company did the testing and where are you doing the comparisons? Ftdna / family finder has a requirement that people share more than 20cM before they show as a match, This can prevent some matches in common from showing. My county Mayo ancestors from the 1820's lived in a small village and I think 1/2 the people in the village shared the same surname and many of them carried the same very common first names. It also looks like there were some cousin marriages and double cousins. RPaine -----Original Message----- From: Patti Hacht via Sent: Saturday, December 19, 2015 7:11 PM To: genealogy-dna@rootsweb.com Subject: [DNA] Three brothers from 1800's and recent DNA matches. I have a question regarding three Irish brothers. For forty plus years I have been researching my Purtell line from near Kilcolman (Shanagolden area) of Co Limerick, Ireland. I discovered my 2nd gr-grandfather, John Purtell b cir 1816 probably in Kilcolman parish. In the Kilcolman Parish rcds, I find a Laurence Purtell who was the sponsor in several of John's children's baptisms. I have thought that Laurence might be John's brother as he was born abt 1810. Laurence emigrated to Binghamton, NY about 1849. About a year later, my John followed Laurence to Binghamton, NY. Within four years, my John had moved further west to Michigan. Then there was a Robert Purtell, said to be related somehow to my John. Robert was born abt 1808 (probably Kilcolman) and emigrated to LaSalette, Ontario, Canada in the 1840's. Members of Robert's family eventually made their way to Midland, Michigan. Enter DNA testing. My brother and my Uncle (who's mother was a Purtell) both DNA match the great grandson of Robert Purtell from LaSalette. (My sister and I do *not* match the LaSalette Purtell's.) And now my brother and "Purtell" uncle also match a descendant of Laurence's from Binghamton. My question is, is there a way (using our DNA matches) to figure out if Robert b 1808, Laurence b 1810 and John b 1816 might have really been brothers? I don't post much to this list because I just don't understand very much about the testing. Thanks for any help, Patti in Lakeville, MIchigan ------------------------------- To unsubscribe from the list, please send an email to GENEALOGY-DNA-request@rootsweb.com with the word 'unsubscribe' without the quotes in the subject and the body of the message ------------------------------- To unsubscribe from the list, please send an email to GENEALOGY-DNA-request@rootsweb.com with the word 'unsubscribe' without the quotes in the subject and the body of the message
Hi Sam, I am self published. Co-authored, and nearly 90 contributors (gratis) to the work. Printed by Gateway Press in Baltimore, I saw some of their work and liked the quality. - Dave Hamm HAM Surname DNA Project coodinator RE: On 12/19/2015 8:43 PM, genealogy-dna-request@rootsweb.com wrote: > Date: Sat, 19 Dec 2015 13:51:18 -0800 > From: Sam Sloan<samhsloan@gmail.com> > Subject: Re: [DNA] My Raw Data Files - Comparison 23andme vs, > AncestryDNA > To: Dave Hamm<odoniv@earthlink.net>, "genealogy-dna@rootsweb.com" > <genealogy-dna@rootsweb.com> > Message-ID: > <CAEaNpccjen-O1JKc532zNAybS4OHzMgStGDEF=Ssny+9KT3WSw@mail.gmail.com> > Content-Type: text/plain; charset=UTF-8 > > Would you be willing to publish this? > > Is it publishable? > > I have a publishing company, Ishi Press. I have published over 700 books. > > Sam Sloan > > On Sat, Dec 19, 2015 at 7:54 AM, Dave Hamm via<genealogy-dna@rootsweb.com> > wrote: > >> >Hello Andreas, >> > >> >Yep, I agree. I have compiled a massive amount of information on my >> >surname in a three volume work, totaling nearly 1200 pages, if memory >> >serves me. Most are the use of my surname in the U.S., but I have some >> >records that also include England and France. >> > >> >Plus, I have a lot of data from my Y-DNA surname project. >> > >> >Most of my autosomal segments only go out to about 4th or 5th cousin. >> >Most of the data that I have an interest in is beyond my 5th cousin. >> >There have been more than one occasion where folks have contacted me >> >about my male line, and I have had to say, "no, that is not my line, >> >that belongs to this other line," etc. (because I have information on a >> >number of branches). >> > >> >I have some 1900 matching autosomal segments, and some 1717 matching >> >segments on chromosome 1, with some 1138 matching segments on chromosome >> >11. My tiny segment studies for my Y-DNA project group tells me that >> >these two chromosomes are my most dense for my 'surname' in haplotype >> >group I1-M253. >> > >> >So, it is standard procedure for me (when I see a large number of >> >matches in a particular area), to look to see who else matches at that >> >location (or, what surnames match at that location). Many times I >> >recognize the 'other' matching segment to a surname that relates to >> >another branch. >> > >> >For example, most recently a person contacted me about triangulating to >> >one of my ancestors. I immediately saw that it was not possible to >> >connect to the tree that I have at FTDNA, nor their tree at Ancestry. I >> >narrowed down my search to triangulating three surnames, plus data from >> >one of the lines in my Y-DNA project. I noticed that we matched that >> >particular start location with two other surnames (HAM, TAYLOR, and >> >PERRY). Several possibilities, but the location and time frame helped >> >narrow the search on that one. (The person who contacted me did not have >> >the correct line. We triangulate to one of my 4th or 5th cousins.) >> > >> >I have a large amount of data on my many 5th cousins which usually >> >includes at least children and spouses. >> > >> >I am getting to the point where I have created software that can tell me >> >what surname bunches into which segments on whatever chromosome. I am >> >getting to the point where I can identify which branch of whatever >> >surname matches whatever branch of my matching surname. >> > >> >So, when I see a large number of matches on a particular segment range >> >then I am a very happy camper. >> > >> > - Dave >> > >> >RE: >> >On 12/18/2015 9:20 PM,genealogy-dna-request@rootsweb.com wrote: >>> > >Date: Sat, 19 Dec 2015 08:35:35 +0700 >>> > >From: Andreas West<ahnen@awest.de> >>> > >Subject: Re: [DNA] My Raw Data Files - Comparison 23andme vs, >>> > > AncestryDNA >>> > >To: David Schroeder<dschroed991@sbcglobal.net>, >>> > > genealogy-dna@rootsweb.com >>> > >Message-ID:<E0E61E4E-8BAC-48CF-A406-929903BBEE0D@awest.de> >>> > >Content-Type: text/plain; charset=us-ascii >>> > > >>> > >We're all related to each other, so pileups are still relatives even >> >though it might back a very long time! >>> > > >>> > >See the WAAH on CHR 2 as an example >>> > > >>> > >Andreas >>> > >