Bonnie, no, I had not seen the article you mentioned, but I have now read it. I see that the authors think the European imprint left in Africans by back migration is most similar to Sardinians, among modern Europeans. Unfortunately, 1000 Genomes doesn't give much sequence data on Sardinians as a group, so it is difficult to assess their Neanderthal SNPs in comparison to the Neanderthal SNPs of other Europeans. Still, it seems unlikely to me that the Neanderthal imprint in Sardinians in the 16,813-bp region that I mentioned would differ by 20 SNPs from that of other Europeans, especially since the number of Neanderthal SNPs among Europeans, South Asians, and East Asians differ from each other by much less than 20 over this 16,813-bp region. So, although I concede that I don't have as much expertise as the authors of the Science paper, I am reluctant to agree that the Neanderthal-related SNPs in Africans can be explained strictly by back migration of Eurasians into Africa. It will be interesting to see what further research shows. On Wed, Dec 23, 2015 at 11:12 AM, Bonnie Schrack via < genealogy-dna@rootsweb.com> wrote: > Hi Obed, > > What an interesting finding. Are you aware of this paper? > "Ancient Ethiopian genome reveals extensive Eurasian admixture > throughout the African continent" > http://www.sciencemag.org/content/350/6262/820 > > Although I appreciate your thinking of our work, it seems just as likely > to me that you have found traces of the Neandertal DNA that was included > in the back-migration to Africa from the Mediterranean-Middle Eastern > region, several thousand years ago. > > I hope we'll all continue to investigate and learn more about this > question! > > Bonnie > > -- > *Farther Back We All Connect* > > ------------------------------- > To unsubscribe from the list, please send an email to > GENEALOGY-DNA-request@rootsweb.com with the word 'unsubscribe' without > the quotes in the subject and the body of the message >

I guess a few hardy "real" genealogists will still be pawing through old records, and arguing about whether an ancestor born 800 years ago was born on a Tuesday or early Wednesday. Genealogist are a hardy breed. I expect they will reinvent a role for themselves doing something. *************** The answer depends on what you want to know. The Mormons call Genealogy Family History--and with good reason. Ancestors should be more than names and dates on a GEDCOM. They lived in a time and place that no longer exists. As the saying goes, the past is a foreign country. The only road way to get there is through historical research. For several years now, I have been doing more historical research than conventional or genetic genealogy and as a result am developing a keen sense of John Britton bc 1672 and the late 17th century Virginia society in which he lived. Primary sources as well as scholarly publications play a necessary role in that research. Life isn't long enough to become acquainted with the many different worlds in which our ancestors lived. Lindsey

In general, John, I agree with you, but there does need to be one other major series of advances in the UK at least. You need to be able to generate optical character recognition and indexing of old handwriting, ideally coupled to an ability to do the same thing for Latin with all it medieval abbreviations. So just different challenges to the next generation! Brian -----Original Message----- From: genealogy-dna-bounces@rootsweb.com [mailto:genealogy-dna-bounces@rootsweb.com] On Behalf Of AJ Marsh via Sent: 03 January 2016 06:30 To: samhsloan@gmail.com; genealogy-dna@rootsweb.com Subject: Re: [DNA] How long will is be before high technology puts us out of business Sam, I agree that full genome sequencing at birth will likely come at some stage.... sooner rather than later. What I have been wondering is how quickly will sophisticated DNA testing kill the hobby of Genealogy? Or can our hobby be killed? If our generation do our job properly, aided by future advances in computer technologies, we will end up with a tolerably complete family tree for the human race, at least for the last half millennium, leaving few mysteries for future genealogists to solve. Future generations will simply input their individual person ID into a tiny computer somehow interfaced with their body, and their past 30 generations of genealogy will spill out from some sort of world supercomputer come super net..... and somehow Ancestry will electronically get forwarded a fee. The Y line will come out complete for the past 500,000 years. If Sykes is still alive, he will have named every one of our ancestors, and the Mormons will have baptised them, every one of them. What will future genealogist have left to do? I guess a few hardy "real" genealogists will still be pawing through old records, and arguing about whether an ancestor born 800 years ago was born on a Tuesday or early Wednesday. Genealogist are a hardy breed. I expect they will reinvent a role for themselves doing something. John. Sent from my iPad > On 3/01/2016, at 4:20 pm, Sam Sloan via <genealogy-dna@rootsweb.com> wrote: > > It is inevitable that at the rate technology is advancing in this > area, if id just a question of time before everybody will know who > their real parents were, whether they want to or not. > It had been suggested that soon every child born will have a full > genome scan done at birth. The doctors will be looking for genetic > defects but if the husband had been cuckolded the doctors will know > right away that he is not the real father even if he suspects nothing. > Will this be a good thing?? > Not only that but anybody going in for any sort of routine medical > checkup will probably have a full genome scan too because the cost > will be so low, so anybody who asks will be told right away who their real parents are. > This is the future. There is no doubt this will happen. My question is > how long will it take for this brave new world to arrive. > I would say that within ten years the technology will be so advanced > that adoption searches will be obsolete. Just as nowadays the doctor > will tell you whether your coming baby will be male or female provided > that you ask, at some future date all you have to do is ask and the > doctors or medical researchers will be able to tell you who your real parents are or were. > How long will this take and will this be a good thing? > Sam Sloan > > ------------------------------- > To unsubscribe from the list, please send an email to > GENEALOGY-DNA-request@rootsweb.com with the word 'unsubscribe' without > the quotes in the subject and the body of the message ------------------------------- To unsubscribe from the list, please send an email to GENEALOGY-DNA-request@rootsweb.com with the word 'unsubscribe' without the quotes in the subject and the body of the message

List A single new mtDNA sequence has appeared on the GenBank database. The sequence is to accompany a new paper (to appear shortly): Zhang,W. and Yao,Y.-G. 'Mitochondrial genome variations and functional characterization in Han Chinese patients with schizophrenia' The sequence belongs to the uncommon subgroup N9a4b As usual I have added the sequence to my 'Checker' program to ensure accuracy of transcription. Ian ------------------------------------ KP668995(China) Zhang N9a4b 31-DEC-2015 A73G C150T A263G 309.1C 315.1C 523.1C 523.2A 523.3C 523.4A A750G A1438G G1664A A2706G A4769G G5231A G5417A C7028T A8860G A9156G G11719A A12358G G12372A C12705T A13242R C14766T A15326G T16092C G16145A T16172C C16223T C16245T C16257A C16261T

But would we care as much about those luscious details if we learn we are not biologically related to those ancestors? I've seen a number of genealogists have to lop off a branch of a well researched tree, with books published, when they discovered they could not possibly be a genetic descendant. On Sun, Jan 3, 2016 at 8:47 AM, Phyllis Garratt via < genealogy-dna@rootsweb.com> wrote: > Just like names, dates and places, knowing who you are related to through > the use of DNA is for me not the core of what genealogy is about. It's an > amazing tool that is incredible, but vital statistics and DNA provide > guideposts and structure to our family trees. The genealogy is in the > luscious colorful details of our ancestors' lives. I would think we're a > long way off from getting that from DNA results, but who knows. > > -----Original Message----- > > email to GENEALOGY-DNA-request@rootsweb.com with the word 'unsubscribe' > without the quotes in the subject and the body of the message >

Just like names, dates and places, knowing who you are related to through the use of DNA is for me not the core of what genealogy is about. It's an amazing tool that is incredible, but vital statistics and DNA provide guideposts and structure to our family trees. The genealogy is in the luscious colorful details of our ancestors' lives. I would think we're a long way off from getting that from DNA results, but who knows. -----Original Message----- > On 3/01/2016, at 4:20 pm, Sam Sloan via <genealogy-dna@rootsweb.com> wrote: > > It is inevitable that at the rate technology is advancing in this > area, if id just a question of time before everybody will know who > their real parents were, whether they want to or not. > I would say that within ten years the technology will be so advanced > that adoption searches will be obsolete. Just as nowadays the doctor > will tell you whether your coming baby will be male or female provided > that you ask, at some future date all you have to do is ask and the > doctors or medical researchers will be able to tell you who your real parents are or were. > How long will this take and will this be a good thing? > Sam Sloan > > ------------------------------- > To unsubscribe from the list, please send an email to > GENEALOGY-DNA-request@rootsweb.com with the word 'unsubscribe' without > the quotes in the subject and the body of the message ------------------------------- To unsubscribe from the list, please send an email to GENEALOGY-DNA-request@rootsweb.com with the word 'unsubscribe' without the quotes in the subject and the body of the message

I can't comment in detail on these matches, although it seems to me that if Polish is showing up strong and is unexpected, chances are there is a Pole in your ancestry (or a collateral relative went to Poland, or something like that). In terms of my own X, or perhaps I should say the X in my tested family members, it is clear that there is strong inheritance from a Scottish ancestor born in 1818. Various of her descendants have tested. That's on my maternal grandfather's side. On my maternal grandmother's, I can't take it farther back than Grandma for certain, although some bits are reasonably certain to be her mother's (more chances of endogamy here). On my paternal grandmother's contribution, again all I can do at this point is say it's Grandma's. The situation isn't helped by the fact that my maternal X is a mix of Scottish and Norwegian while the paternal X is all Norwegian (with bits of old Finnish) and that most of my tested known relatives are also half or more Norwegian. Still, it's exciting to have separated out the Scottish from the 1818 ancestor. I wish I knew which other Scottish contributors put in their bits, as my X should be about 1/4 Scottish and she should account for about half of that. On Sat, Jan 2, 2016 at 11:27 PM, steven perkins via < genealogy-dna@rootsweb.com> wrote: > Below are my male to male X matches at 23andMe with cM, SNP counts and > relationship degree if known: > > Hopefully this table will come through in a readable condition. > > 2.3 297 2c 1r > 2.4 304 > 3 336 3c > 3.1 339 > 4 316 > 4.3 325 > 5.1 365 5c > 5.4 441 > 6 448 3c 1r > 7.8 900 > 8.2 671 > 8.2 785 > 8.2 785 > 12.6 1506 > 13 1334 > 13 687 > 13.4 882 > 13.4 882 > 13.6 1114 > 13.9 1124 > 15.2 1771 > 30.2 2468 > 30.4 2462 > 36.2 2960 > > ​ > 48.2 > ​ ​ > 4359 > > > > > > > ​ > > ​ > ​Any suggestions which are real matches? > > Except for the four where I know how we are related I'm stumped with the > others. > > One is in England, one is in Canada, and one is mainly Polish with a > surname that appears in one of my autosomal matches on his mother's side, > her ancestry is all Polish and his paternal surnames do not match my > ancestors but he is from an area where I had family in the 1600s through > the 1700s. > > There are two brothers in the list and I match them and their mother, but > the mother's ancestry is recent German. We do share a surname in her > ancestry but it is not one that is in the female X inheritance pattern. > > My last English immigrant was in the early 1770s and I have no known Polish > ancestry but Poland is a high entry in my COA lists. I have at lest two > German surnames. > > Two other people appear on this list twice. We do have surnames in common, > but neither one has posted a pedigree. > > A few of them also share autosomal ancestry with me, but most share only on > the X. > > The first match is a second cousin once removed. His mother does not show > as an X match, but I believe that is because of the different standards for > a male to female X match at 23andme. > > Any one else tried this kind of analysis? > > Happy New Year to all! > > Steven > > ​ > > > > > > > > > > > -- > Steven C. Perkins SCPerkins@gmail.com http://stevencperkins.com/ > Indigenous Peoples' Rights http://intelligent-internet.info/law/ipr2.html > Indigenous & Ethnic Minority Legal News http://iemlnews.blogspot.com/ > Online Journal of Genetics and Genealogy http://jgg-online.blogspot.com/ > S.C. Perkins' Genealogy Page http://stevencperkins.com/genealogy.html > S.C. Perkins' Genealogy Blog http://scpgen.blogspot.com/ > > ------------------------------- > To unsubscribe from the list, please send an email to > GENEALOGY-DNA-request@rootsweb.com with the word 'unsubscribe' without > the quotes in the subject and the body of the message -- Karla Huebner calypsospots AT gmail.com

Absolutely. Thanks for spreading the word. Thomas On 01/03/2016 02:31 AM, Kitty Cooper wrote: > Can I add this information to my blog post on this? Or even do another > post > I am personally fascinated by all this ... > > http://blog.kittycooper.com/2015/12/end-of-year-giving/ > > > > --------------------------------------------------------------- > Kitty Munson Cooper, web developer,programmer, San Diego,CA > > genetic genealogy blog at http://blog.kittycooper.com/ > family history and genealogy at http://kittymunson.com > > On Sat, Jan 2, 2016 at 1:46 PM, Thomas Krahn via > <genealogy-dna@rootsweb.com <mailto:genealogy-dna@rootsweb.com>> wrote: > > New Year Challenge: R1b in Cameroon > > Among our samples collected by Mathew on his last field trips we have > found the following two haplotypes: > > http://www.yseq.net/R1bCameroonChallenge.html > > Note that Y-GATA-H4 is in the NIST standard. If you want to > compare them > to FTDNA you need to subtract 1. The haplogroup predictors clearly > claim > 100% R1b. > > Now the question is: How did those two Y chromosomes find their way to > Sub-Saharan Africa? Could it be that some Europeans have left their > traces during colonization times? > > Well, if you're familiar with R1b in Europe, the haplotypes still > look a > little bit strange. > > Also we keep finding R1b distribution maps that highlight an R1b > hot-spot in Northern Cameroon: > http://www.eupedia.com/europe/Haplogroup_R1b_Y-DNA.shtml > https://en.wikipedia.org/wiki/Haplogroup_R1b > > Wikipedia characterizes the hotspot in Northern Cameroon as R1b-V88. > However V88 is in a region of the Y chromosome that is 97.9% identical > to ChrX, so it wouldn't qualify for a stable marker according to the > newest ISOGG guidelines. I'd rather prefer to test stable known SNPs > that independently proof the association with the North African and > Arabic regions. > > I'd like to involve you, the R1b experts to use your knowledge and > experience to solve this mystery in a group effort. At the same > time I'd > like to give the A00 Cameroon Research Project another push for > donations. > > So here are the rules of the game: > > YSEQ will do free SNP tests on those 2 samples if you donate an equal > amount ($17.50 per SNP) to Bonnie Schrack's A00 Cameroon Research > project. > > http://experiment.com/a00west > > When you make the donation, send Bonnie and myself an email > thomas@yseq.net <mailto:thomas@yseq.net>, bonnieschrack@gmail.com > <mailto:bonnieschrack@gmail.com> with the marker you want to > sponsor and the YSEQ ID it should be tested for. The marker must be > available in the YSEQ catalog: > > https://www.yseq.net/ > > or at least we must have the primers in stock so that we can quickly > test them. Ask us for a distinct SNP if you're unsure. > > We will process the SNPs in the very next batch and release the > results > to the public. You can keep sponsoring the next round when the results > come in. But note that the A00 Cameroon project deadline at > experiment.com <http://experiment.com> is on January 6th! So there > are only 5 days left to > submit your suggested SNP and the associated sample ID. > > The Prize: > > The researcher who submits the most downstream positive SNP first will > win a free Haplogroup Panel at YSEQ which he can use for a person > of his > choice. Since there are two samples, there are two Haplogroup Panels > that you can win! > > Good luck and Happy New Year! > > Thomas > > ------------------------------- > To unsubscribe from the list, please send an email to > GENEALOGY-DNA-request@rootsweb.com > <mailto:GENEALOGY-DNA-request@rootsweb.com> with the word > 'unsubscribe' without the quotes in the subject and the body of > the message > >

I was looking at the https://www.fullgenomes.com site today and see they have listed amongst their tests a Molgen-FGC Project and Buchanan Project. I couldn't find any descriptions of them on the web site. Does anyone know what these projects are about, or if this is a sign of FGC working to incorporating "Projects" of some kind into their system? John. Sent from my iPad

Steven Most of my male-male X-matches are similar in size to yours but my match with my male maternal 1st cousin is very large: 143 cM, 11566SNPs This appears to be from our maternal grandfather's mother born 1861 and reaches back into the mountains of West Virginia. Many of my X-matches list Robinson ancestors He only shares a 21.4cM X-match with his full sister, while I share that segment with her and a 40cM segment. RPaine -----Original Message----- From: steven perkins via Sent: Saturday, January 2, 2016 8:27 PM To: genealogy-dna Subject: [DNA] Male X matches at 23andMe Below are my male to male X matches at 23andMe with cM, SNP counts and relationship degree if known: Hopefully this table will come through in a readable condition. 2.3 297 2c 1r 2.4 304 3 336 3c 3.1 339 4 316 4.3 325 5.1 365 5c 5.4 441 6 448 3c 1r 7.8 900 8.2 671 8.2 785 8.2 785 12.6 1506 13 1334 13 687 13.4 882 13.4 882 13.6 1114 13.9 1124 15.2 1771 30.2 2468 30.4 2462 36.2 2960 48.2 4359 ​Any suggestions which are real matches? Except for the four where I know how we are related I'm stumped with the others. One is in England, one is in Canada, and one is mainly Polish with a surname that appears in one of my autosomal matches on his mother's side, her ancestry is all Polish and his paternal surnames do not match my ancestors but he is from an area where I had family in the 1600s through the 1700s. There are two brothers in the list and I match them and their mother, but the mother's ancestry is recent German. We do share a surname in her ancestry but it is not one that is in the female X inheritance pattern. My last English immigrant was in the early 1770s and I have no known Polish ancestry but Poland is a high entry in my COA lists. I have at lest two German surnames. Two other people appear on this list twice. We do have surnames in common, but neither one has posted a pedigree. A few of them also share autosomal ancestry with me, but most share only on the X. The first match is a second cousin once removed. His mother does not show as an X match, but I believe that is because of the different standards for a male to female X match at 23andme. Any one else tried this kind of analysis? Happy New Year to all! Steven -- Steven C. Perkins SCPerkins@gmail.com http://stevencperkins.com/ Indigenous Peoples' Rights http://intelligent-internet.info/law/ipr2.html Indigenous & Ethnic Minority Legal News http://iemlnews.blogspot.com/ Online Journal of Genetics and Genealogy http://jgg-online.blogspot.com/ S.C. Perkins' Genealogy Page http://stevencperkins.com/genealogy.html S.C. Perkins' Genealogy Blog http://scpgen.blogspot.com/ ------------------------------- To unsubscribe from the list, please send an email to GENEALOGY-DNA-request@rootsweb.com with the word 'unsubscribe' without the quotes in the subject and the body of the message

Below are my male to male X matches at 23andMe with cM, SNP counts and relationship degree if known: Hopefully this table will come through in a readable condition. 2.3 297 2c 1r 2.4 304 3 336 3c 3.1 339 4 316 4.3 325 5.1 365 5c 5.4 441 6 448 3c 1r 7.8 900 8.2 671 8.2 785 8.2 785 12.6 1506 13 1334 13 687 13.4 882 13.4 882 13.6 1114 13.9 1124 15.2 1771 30.2 2468 30.4 2462 36.2 2960 ​ 48.2 ​ ​ 4359 ​ ​ ​Any suggestions which are real matches? Except for the four where I know how we are related I'm stumped with the others. One is in England, one is in Canada, and one is mainly Polish with a surname that appears in one of my autosomal matches on his mother's side, her ancestry is all Polish and his paternal surnames do not match my ancestors but he is from an area where I had family in the 1600s through the 1700s. There are two brothers in the list and I match them and their mother, but the mother's ancestry is recent German. We do share a surname in her ancestry but it is not one that is in the female X inheritance pattern. My last English immigrant was in the early 1770s and I have no known Polish ancestry but Poland is a high entry in my COA lists. I have at lest two German surnames. Two other people appear on this list twice. We do have surnames in common, but neither one has posted a pedigree. A few of them also share autosomal ancestry with me, but most share only on the X. The first match is a second cousin once removed. His mother does not show as an X match, but I believe that is because of the different standards for a male to female X match at 23andme. Any one else tried this kind of analysis? Happy New Year to all! Steven ​ -- Steven C. Perkins SCPerkins@gmail.com http://stevencperkins.com/ Indigenous Peoples' Rights http://intelligent-internet.info/law/ipr2.html Indigenous & Ethnic Minority Legal News http://iemlnews.blogspot.com/ Online Journal of Genetics and Genealogy http://jgg-online.blogspot.com/ S.C. Perkins' Genealogy Page http://stevencperkins.com/genealogy.html S.C. Perkins' Genealogy Blog http://scpgen.blogspot.com/

New Year Challenge: R1b in Cameroon Among our samples collected by Mathew on his last field trips we have found the following two haplotypes: http://www.yseq.net/R1bCameroonChallenge.html Note that Y-GATA-H4 is in the NIST standard. If you want to compare them to FTDNA you need to subtract 1. The haplogroup predictors clearly claim 100% R1b. Now the question is: How did those two Y chromosomes find their way to Sub-Saharan Africa? Could it be that some Europeans have left their traces during colonization times? Well, if you're familiar with R1b in Europe, the haplotypes still look a little bit strange. Also we keep finding R1b distribution maps that highlight an R1b hot-spot in Northern Cameroon: http://www.eupedia.com/europe/Haplogroup_R1b_Y-DNA.shtml https://en.wikipedia.org/wiki/Haplogroup_R1b Wikipedia characterizes the hotspot in Northern Cameroon as R1b-V88. However V88 is in a region of the Y chromosome that is 97.9% identical to ChrX, so it wouldn't qualify for a stable marker according to the newest ISOGG guidelines. I'd rather prefer to test stable known SNPs that independently proof the association with the North African and Arabic regions. I'd like to involve you, the R1b experts to use your knowledge and experience to solve this mystery in a group effort. At the same time I'd like to give the A00 Cameroon Research Project another push for donations. So here are the rules of the game: YSEQ will do free SNP tests on those 2 samples if you donate an equal amount ($17.50 per SNP) to Bonnie Schrack's A00 Cameroon Research project. http://experiment.com/a00west When you make the donation, send Bonnie and myself an email thomas@yseq.net, bonnieschrack@gmail.com with the marker you want to sponsor and the YSEQ ID it should be tested for. The marker must be available in the YSEQ catalog: https://www.yseq.net/ or at least we must have the primers in stock so that we can quickly test them. Ask us for a distinct SNP if you're unsure. We will process the SNPs in the very next batch and release the results to the public. You can keep sponsoring the next round when the results come in. But note that the A00 Cameroon project deadline at experiment.com is on January 6th! So there are only 5 days left to submit your suggested SNP and the associated sample ID. The Prize: The researcher who submits the most downstream positive SNP first will win a free Haplogroup Panel at YSEQ which he can use for a person of his choice. Since there are two samples, there are two Haplogroup Panels that you can win! Good luck and Happy New Year! Thomas

It is inevitable that at the rate technology is advancing in this area, if id just a question of time before everybody will know who their real parents were, whether they want to or not. It had been suggested that soon every child born will have a full genome scan done at birth. The doctors will be looking for genetic defects but if the husband had been cuckolded the doctors will know right away that he is not the real father even if he suspects nothing. Will this be a good thing?? Not only that but anybody going in for any sort of routine medical checkup will probably have a full genome scan too because the cost will be so low, so anybody who asks will be told right away who their real parents are. This is the future. There is no doubt this will happen. My question is how long will it take for this brave new world to arrive. I would say that within ten years the technology will be so advanced that adoption searches will be obsolete. Just as nowadays the doctor will tell you whether your coming baby will be male or female provided that you ask, at some future date all you have to do is ask and the doctors or medical researchers will be able to tell you who your real parents are or were. How long will this take and will this be a good thing? Sam Sloan

Can I add this information to my blog post on this? Or even do another post I am personally fascinated by all this ... http://blog.kittycooper.com/2015/12/end-of-year-giving/ --------------------------------------------------------------- Kitty Munson Cooper, web developer,programmer, San Diego,CA genetic genealogy blog at http://blog.kittycooper.com/ family history and genealogy at http://kittymunson.com On Sat, Jan 2, 2016 at 1:46 PM, Thomas Krahn via <genealogy-dna@rootsweb.com > wrote: > New Year Challenge: R1b in Cameroon > > Among our samples collected by Mathew on his last field trips we have > found the following two haplotypes: > > http://www.yseq.net/R1bCameroonChallenge.html > > Note that Y-GATA-H4 is in the NIST standard. If you want to compare them > to FTDNA you need to subtract 1. The haplogroup predictors clearly claim > 100% R1b. > > Now the question is: How did those two Y chromosomes find their way to > Sub-Saharan Africa? Could it be that some Europeans have left their > traces during colonization times? > > Well, if you're familiar with R1b in Europe, the haplotypes still look a > little bit strange. > > Also we keep finding R1b distribution maps that highlight an R1b > hot-spot in Northern Cameroon: > http://www.eupedia.com/europe/Haplogroup_R1b_Y-DNA.shtml > https://en.wikipedia.org/wiki/Haplogroup_R1b > > Wikipedia characterizes the hotspot in Northern Cameroon as R1b-V88. > However V88 is in a region of the Y chromosome that is 97.9% identical > to ChrX, so it wouldn't qualify for a stable marker according to the > newest ISOGG guidelines. I'd rather prefer to test stable known SNPs > that independently proof the association with the North African and > Arabic regions. > > I'd like to involve you, the R1b experts to use your knowledge and > experience to solve this mystery in a group effort. At the same time I'd > like to give the A00 Cameroon Research Project another push for donations. > > So here are the rules of the game: > > YSEQ will do free SNP tests on those 2 samples if you donate an equal > amount ($17.50 per SNP) to Bonnie Schrack's A00 Cameroon Research project. > > http://experiment.com/a00west > > When you make the donation, send Bonnie and myself an email > thomas@yseq.net, bonnieschrack@gmail.com with the marker you want to > sponsor and the YSEQ ID it should be tested for. The marker must be > available in the YSEQ catalog: > > https://www.yseq.net/ > > or at least we must have the primers in stock so that we can quickly > test them. Ask us for a distinct SNP if you're unsure. > > We will process the SNPs in the very next batch and release the results > to the public. You can keep sponsoring the next round when the results > come in. But note that the A00 Cameroon project deadline at > experiment.com is on January 6th! So there are only 5 days left to > submit your suggested SNP and the associated sample ID. > > The Prize: > > The researcher who submits the most downstream positive SNP first will > win a free Haplogroup Panel at YSEQ which he can use for a person of his > choice. Since there are two samples, there are two Haplogroup Panels > that you can win! > > Good luck and Happy New Year! > > Thomas > > ------------------------------- > To unsubscribe from the list, please send an email to > GENEALOGY-DNA-request@rootsweb.com with the word 'unsubscribe' without > the quotes in the subject and the body of the message >

List Catching up ... So here are the final sequences from this set. These sequences are marked 'N1c' & 'N1e' - labels which might be appearing on the new 'phylotree' due out shortly. Ian www.ianlogan.co.uk ---------------- JX134998(India) Palanichamy Haplogroup N1c 07-DEC-2015 A73G G143A A189G T195C T204C G207A A210G A263G 315.1C A750G A1438G G1719A A2706G A4769G A5581G A6677G C7028T T8222C A8860G T10238C C10619T T11025C T11437C G11719A G11914A G12501A C12705T A13637G A13780G C14766T A15326G C16201T C16223T T16519C JX134999(USA) Palanichamy Haplogroup N1c 07-DEC-2015 A73G A189G T195C T204C G207A A210G A263G 309.1C T596C A750G A1438G G1719A A2706G A4769G C7028T T8222C A8860G T10238C C10553T T11025C T11437C G11719A G12501A C12705T A13637G A13780G C14766T A15326G G16145A C16201T C16223T A16265G T16519C JX135000(USA) Palanichamy Haplogroup N1c 07-DEC-2015 A73G T152C A189G T195C T204C G207A A263G 315.1C C522- A523- A750G A1438G G1719A A2706G G3591A A3672T A4769G G5460A G6261A C7028T T7861C T8222C A8860G T10238C T11025C T11437C G11719A G11914A G12501A C12705T A13637G A13780G C14766T A15326G C16201T C16223T C16259T A16265G C16270G G16319A T16519C JX135001(India) Palanichamy Haplogroup N1c 07-DEC-2015 A73G T152C A189G T195C C198T G207A A210G A263G 315.1C A750G A1438G G1719A A2706G A4769G A5319G C7028T T8222C A8308G A8860G C8943T T9084C T10238C T11025C T11437C G11719A G11914A G12501A A12612G C12705T A13637G A13780G G14560A C14766T A15326G T16086C C16201T C16223T A16265G C16355T T16519C JX135002(India) Palanichamy Haplogroup N1e 07-DEC-2015 A73G G143A T199C T204C T250C A263G 315.1C 573.1C T710C A750G A1438G G1719A A2706G T3645A A4529T A4769G A6932G C7028T G8251A A8860G T10238C A10388G A10398G T10790C T11204C G11719A A12361G G12501A C12705T A13748G A13780G C14766T G15043A A15326G A15924G G15930A C16223T A16309G T16311C G16391A T16519C JX135003(India) Palanichamy Haplogroup N1e 07-DEC-2015 A73G G143A T199C T204C T250C A263G A297G 315.1C 573.1C T710C A750G A1438G G1719A A2706G A4529T A4769G T4947C T6671C C7028T G8251A A8860G T10238C A10398G T10790C T10882C G11719A G12501A C12705T A13780G C14766T G15043A A15326G A15924G A15954G C16223T T16311C G16391A T16519C

I saw them too. Haven't asked Justin about them ... but it seems a good idea for group of similar haplotypes to "band together" and support each other doing full genome testing ... Al On Sat, Jan 2, 2016 at 4:11 AM, AJ Marsh via <genealogy-dna@rootsweb.com> wrote: > I was looking at the https://www.fullgenomes.com site today and see they > have listed amongst their tests a Molgen-FGC Project and Buchanan Project. > I couldn't find any descriptions of them on the web site. Does anyone know > what these projects are about, or if this is a sign of FGC working to > incorporating "Projects" of some kind into their system? > > John. > > Sent from my iPad > > ------------------------------- > To unsubscribe from the list, please send an email to > GENEALOGY-DNA-request@rootsweb.com with the word 'unsubscribe' without > the quotes in the subject and the body of the message >

List Catching up stilll .... here are more sequences from this set. Ian www.ianlogan.co.uk ----------------- GQ337616 Palanichamy Haplogroup M2a3a 07-DEC-2015 A73G T146C A263G 309.1C 315.1C C447G T489C 523.1C 523.2A A750G A1438G T1780C A2706G A4769G T5426C T5774C C7028T G7762A T7961C A8502G A8701G G8838A A8860G T9540C A10398G C10400T T10873C A11083G T11383C G11719A G12127A C12705T A12810G C14766T T14783C G15043A G15301A A15326G T15670C C16223T A16265C G16274A G16319A T16519C GQ337617 Palanichamy Haplogroup M40 07-DEC-2015 A73G G185A A263G 309.1C 315.1C T489C A750G T789C A1438G A2706G A4769G G6755A C7028T A8701G A8860G A8925G T9540C A10398G C10400T T10873C G11719A C12705T A13542G C14766T T14783C G15043A T15229C G15301A A15326G T15721C A15954G C16179T C16223T C16294T T16325C A16463G GQ337618 Palanichamy Haplogroup M66a 07-DEC-2015 A73G T195C A263G 309.1C 309.2C 315.1C T489C 523.1C 523.2A A750G A1438G G1888A A2706G G4541A A4769G T6221C T6827C C7028T A8701G A8860G C9061T T9540C A10398G C10400T T10873C G11719A G12007A G12501A C12705T C14766T T14783C G15043A G15301A A15326G C16184T T16189C C16223T T16249C T16519C GQ337619 Palanichamy Haplogroup M66a 07-DEC-2015 A73G T195C A263G 309.1C 309.2C 315.1C T489C 523.1C 523.2A A750G A1438G G1888A A2706G G4541A A4769G T6221C T6827C C7028T A8701G A8860G C9061T T9540C A10398G C10400T T10873C G11719A G12007A G12501A C12705T C14766T T14783C G15043A G15301A A15326G C16184T T16189C C16223T T16249C T16519C GQ337620 Palanichamy Haplogroup U2a1b 07-DEC-2015 A73G A189G A200G A263G 315.1C A750G 960.1C T1119C A1438G A1585G A1811G A2706G A4769G A4944G A6701G C7028T C7170T A8860G G9932A T11383C A11467G G11719A G12372A A12715G G13708A C13947T C14766T A15326G A16051G T16093C A16180G A16206C A16230G T16311C C16353T GQ337621 Palanichamy Haplogroup M3d1a 07-DEC-2015 A73G T146C A263G 309.1C 315.1C T482C T489C A750G A1438G A2706G A4769G G6383A C7028T A8701G A8860G T9540C T10238C A10398G C10400T T10873C A11084G G11719A T11827C C12705T C12813T G13359A T13820C C14766T T14783C G15043A G15301A A15326G T16126C C16223T C16344T T16519C GQ337622 Palanichamy Haplogroup M2c 07-DEC-2015 A73G G185A T199C A263G 309.1C 315.1C C447G T489C A750G A1438G G1598A T1780C A2706G G3591A T4216C A4769G C7028T A7325G A8701G A8860G T9540C A10398G C10400T T10873C A11083G G11719A C12705T G13194A C13212T C14766T T14767C T14783C C14800T G14861A G15043A G15301A A15326G T15670C T16093C C16223T A16258- G16274A GQ337624 Palanichamy Haplogroup M2a1 07-DEC-2015 A73G G203A T204C A263G 309.1C 315.1C C447A T489C A750G A1438G T1780C A2706G A4769G G5252A G6917A C7028T T7961C A8396G A8502G A8701G A8860G T9540C T9758C A10398G C10400T T10873C A11083G G11719A T11792G T11984C C12705T A12810G C14766T T14783C G15043A G15301A A15326G T15670C C16223T C16270T G16274A G16319A T16352C T16519C GQ337625 Palanichamy Haplogroup M33a2 07-DEC-2015 A73G A200G A263G 315.1C T318C C462T T489C C522- A523- A750G A1438G A1978C G2361A A2706G A4769G A5423G C7028T A8041G C8562T A8701G A8860G T9540C A10398G C10400T T10873C G11719A A12373G C12705T A13731G C14766T T14783C G15043A G15301A G15317A A15326G T15908C C16169T T16172C C16223T T16519C GQ337626 Palanichamy Haplogroup U2b1 07-DEC-2015 T51C T57A T58G 60.1T A73G T146C A263G 309.1C 315.1C C522- A523- A750G A1438G A1811G G3693A G3915A A4093G A4769G A5186T C7028T G8251A T8490C A8860G T9647C G11016A A11467G G11719A C12106T A12308G G12372A G13194A G13759A C14766T A14769G C15049T A15326G A16051G T16092C C16168T T16519C GQ337627 Palanichamy Haplogroup U2b1 07-DEC-2015 A73G T146C A263G 309.1C 315.1C C522- A523- A750G A1438G G1709A A1811G T1822C G3915A A4093G A4769G T4772C G4820A A5186T C7028T T7609C G7805A A8679C A8860G T10248C A11467G G11719A A11800G C12106T G12127A A12308G G12372A G13194A G14016A C14766T C15049T A15326G A15607G A16051G C16168T C16278T T16311C T16519C GQ337628 Palanichamy Haplogroup R31a 07-DEC-2015 A73G T146C T217C A263G 315.1C 315.2C C338T C522- A523- A750G A1438G C1531T A2706G A4769G C5348T G6480A C7028T A7295G C7981T A8860G G10373A C10631T G11719A A13557G T13768A C14553T C14766T A15326G T16093C T16304C T16519C GQ337629 Palanichamy Haplogroup M33b1 07-DEC-2015 A73G A263G 309.1C 315.1C T489C 523.1C 523.2A G676A A750G A1438G G1719A G2361A A2706G A3221G A4769G C4814T T6092C T6293C C7028T A8701G A8860G T9540C A10398G C10400T T10724C T10873C G11719A C12705T A14693G C14766T T14783C G15043A G15301A A15326G C16223T C16259T G16319A T16324C T16362C T16519C GQ337630 Palanichamy Haplogroup M33a 07-DEC-2015 A73G C150T A263G T293C 309.1C 315.1C T489C A750G A1438G G2361A A2706G A2833G T4117C A4769G A5505G C7028T C8562T A8701G A8860G T9540C G10310A A10398G C10400T T10873C G11719A C12705T T13437C T14290C C14766T T14783C G15043A G15301A A15326G T15908C A16316G G16319A T16519C GQ337631 Palanichamy Haplogroup R31a 07-DEC-2015 A73G C258T A263G 315.1C 315.2C 315.3C C522- A523- 573.1C 573.2C A750G A1438G C1531T A2706G A4769G C7028T C7981T G8387A A8860G G9380A A9632G G11719A G12236C A13557G C14553T C14766T A14927G A15326G T16217C T16304C T16519C GQ337632 Palanichamy Haplogroup U2b1 07-DEC-2015 A73G T146C A263G 309.1C 315.1C C522- A523- A750G A1438G A1811G G3915A A4093G C4637T A4769G A5186T A5966G C7028T A8860G A11467G G11719A C11743T C12106T A12308G A12367G G12372A T12609C A13105G G13194A T14374C C14766T C15049T A15326G A16051G A16318G GQ337633 Palanichamy Haplogroup M20 07-DEC-2015 A73G T152C G225A A249- A263G 309.1C 315.1C G316A T489C C522- A523- A750G A1438G A2706G T3200C A3714G A4385T A4769G T4772C A6272G C7028T C7433T A8701G A8853G A8860G C8940T G9064A A9127G C9512T T9540C T10274C A10398G C10400T A10679G T10873C G11719A G11914A T12354C A12373G C12705T T14110C C14766T T14783C C14974T G15043A G15301A A15326G A15691G G16129A T16209C C16223T A16272G T16362C T16519C GQ337634 Palanichamy Haplogroup M5a 07-DEC-2015 T55C T57G A73G A263G 315.1C T489C G709A A750G 960.1C T1391C A1438G G1888A A2706G C3921T A4769G C7028T A8701G A8860G T9540C A10398G C10400T T10873C G11719A T12477C C12705T G14323A C14766T T14783C G15043A G15301A A15326G G15731A G16129A T16172C C16223T C16301T T16519C GQ337635 Palanichamy Haplogroup M50 07-DEC-2015 A73G C150T A263G 309.1C 315.1C A326G C456T T489C C522- A523- A750G A1383G A1438G A2706G C3417T A4769G T6092C C7028T G7226A A8701G T8802C A8860G T9540C A10398G C10400T T10873C G11719A C12281T C12486T C12705T C13914T C14766T T14783C G15043A T15055C G15301A A15326G A15607G T15663C A16166C T16172C C16174T C16223T 16262.1C T16263C A16309G G16319A G16526A GQ337636 Palanichamy Haplogroup M45a 07-DEC-2015 A73G T146C T152C T199C A263G 309.1C 315.1C T489C C679T A750G A1438G A2706G T3083C C4059A A4734G A4769G A5319G G5585A T6827C C7028T A8701G A8860G T9095C A9180G T9509C T9540C A10398G C10400T T10873C G11719A G12007A C12705T A14687G C14766T T14783C G15043A G15301A A15326G A15769G T16093C C16192T C16223T A16300G A16316G T16519C GQ337637 Palanichamy Haplogroup M45a 07-DEC-2015 A73G T146C T152C A263G 309.1C 315.1C T489C A750G A1438G A4734G A4769G A6872G C7028T A7049G T7645C G8557A A8701G A8860G A9180G T9540C G10310A A10398G C10400T T10873C G11719A G11914A G12007A C12705T T14212C C14766T T14783C G15043A G15301A A15326G C15604T A15836G T16189C C16223T A16300G G16319A T16519C GQ337638 Palanichamy Haplogroup M52b1 07-DEC-2015 A73G A263G T310- C313- C314- C315- T489C C522- A523- A750G A1438G G1462T G1598A A2706G G3745A A4760G A4769G G5460A C6020T C7028T G8557A A8701G A8860G T9540C A10398G C10400T A10750G T10873C G11719A C12705T C13815T C14623A C14766T T14783C G15043A G15301A A15326G C15815T G16129A A16182- A16183- T16189C 16193.1C 16193.2C C16223T A16275G T16311C G16438A GQ337639 Palanichamy Haplogroup M39c 07-DEC-2015 55.1T T59- T60- 65.1T 65.2G G71- A73G A263G 309.1C 315.1C T489C A750G A1438G A1811G A2706G A4012G A4769G C7028T A8679G A8701G A8860G T9540C G9575A G9921A A10188G A10398G C10400T C10619T T10873C G11719A C12705T C14766T T14783C G15043A G15172A G15301A A15326G C15589A C15938T C16223T A16272G T16325C GQ337640 Palanichamy Haplogroup M45a 07-DEC-2015 A73G T146C C150T T152C G260A A263G 309.1C 309.2C 315.1C T489C A750G A1438G A4734G A4769G A6872G C7028T A7049G T7645C A8701G A8860G A9180G T9540C A10398G C10400T T10873C G11719A G11914A G12007A C12705T A12990G T14212C C14766T T14783C G15043A G15301A A15326G A16183- T16189C 16193.1C A16300G T16519C GQ337641 Palanichamy Haplogroup M41b 07-DEC-2015 A73G A263G 315.1C C375T T489C A750G C870T A1438G A2706G A4769G T6297C C7028T A8701G A8860G T9540C A10398G C10400T T10873C G11719A C12398T A12469G C12705T T13656C T13768C C14766T T14783C G15043A G15301A A15326G A15442G T15601C C16223T C16327T T16330C T16519C GQ337642 Palanichamy Haplogroup M18b 07-DEC-2015 A73G T146C T246C A263G 315.1C T489C A750G A1438G A2706G G4132A A4769G A5153G C7028T 8276.1C 8276.2C T8277C T8279C A8701G A8860G T9540C A10398G C10400T T10873C G11719A G12007A C12498T C12705T G13135A A14587G C14766T T14783C G15043A G15301A A15326G C16223T A16318T T16325C T16519C GQ337643 Palanichamy Haplogroup M2a3 07-DEC-2015 A73G T146C A263G 309.1C 315.1C C447G T489C A750G A1438G T1780C A2706G A4769G T5426C T5774C C7028T G7762A T7961C A8502G A8701G A8860G G9055A T9540C A10398G C10400T T10873C A11083G A11167G T11260C T11353C G11719A C12705T A12810G G14259A C14766T T14783C G15043A G15301A A15326G T15670C T16189C C16223T C16261T G16274A T16311C G16319A T16519C GQ337644 Palanichamy Haplogroup M45a 07-DEC-2015 A73G G143A T146C T152C A263G 315.1C T489C C534T A750G A1438G A4734G A4769G C5349T A6872G C7028T A7049G A8701G A8860G A9180G T9540C A10398G C10400T T10873C G11719A G12007A C12705T T14212C C14766T T14783C G15043A G15301A A15326G T16189C C16192T C16223T A16300G T16519C GQ337645 Palanichamy Haplogroup M5a 07-DEC-2015 A73G T154C A263G 309.1C 315.1C T489C G709A A750G A1438G G1888A A2706G C3921T A4769G C7028T A8701G A8860G T9540C A10398G C10400T G10589A T10873C G11719A T12477C T12481C T12681C C12705T G14323A C14766T T14783C G15043A G15301A A15326G T16172C C16223T T16356C T16519C GQ337646 Palanichamy Haplogroup M 07-DEC-2015 A73G A243G A263G 309.1C 315.1C T489C A750G A1438G A2706G G3010A A3729C A4769G T5130C T5483C T6152C C7028T G8519A A8701G A8860G T9540C A10398G C10400T T10873C A11101G G11719A C12705T G12795A C14766T T14783C G15043A T15090C A15244G G15301A A15326G T16189C C16223T T16243C T16519C GQ337647 Palanichamy Haplogroup R 07-DEC-2015 A73G T152C A263G 309.1C 315.1C G513A A750G A1438G A2706G A3816G A4769G G4820A T5201C C7028T A8149G G8269A C8464T A8501T A8784G A8860G A8887G T9116C T10454C G11719A G12771A C14766T A15326G A15712G T16092C G16145A C16185T C16239T T16325C T16519C GQ337648 Palanichamy Haplogroup M43b 07-DEC-2015 A73G A263G 315.1C T489C G709A A750G A1438G A2706G A4769G C5444A C7028T A8701G A8860G G8950A T9540C A10316G A10398G C10400T T10873C G11696A G11719A G12007A C12636T C12705T T14488C C14766T T14783C G15043A G15148A G15301A A15326G G16000T T16092C C16223T T16519C GQ337649 Palanichamy Haplogroup M51a 07-DEC-2015 A73G T146C C150T T152C A263G C269T 309.1C 315.1C T489C C522- A523- A750G A1438G A2706G C4697T A4769G T4907C T4973C C7028T A8701G A8860G T9509C T9540C A10398G C10400T T10873C G11719A G11963A G12236A C12705T T14110C C14356T A14687G C14766T T14783C G15043A G15301A G15317A A15326G A15534G A16037G C16223T C16278T T16311C C16320T T16519C GQ337650 Palanichamy Haplogroup M21b 07-DEC-2015 A73G G143A T152C A263G 309.1C 309.2C 315.1C T489C C496A A750G T980C A1438G A2706G G3915A A4769G T5108C G5460A C7028T T7861C A8701G A8860G T9540C A10398G C10400T T10873C T11260C T11482C G11719A C12705T A13966G C14766T T14783C G15043A G15301A A15326G G16042A A16070G A16183- T16189C 16193.1C 16193.2C T16209C C16223T A16233G T16519C GQ337651 Palanichamy Haplogroup M50 07-DEC-2015 A73G T146C C150T C151T T152C A263G 309.1C 315.1C T489C C522- A523- A750G A1438G A2706G G3316A A4769G C7028T G7226A A8701G A8860G T9540C A9608G A10398G C10400T C10538A T10873C T11365C G11719A C12705T T14182C C14766T T14783C G15043A G15301A A15326G C15616T T15663C T16093C T16209C C16223T T16224C T16263C C16278T G16319A GQ337652 Palanichamy Haplogroup M22b 07-DEC-2015 A73G A263G 309.1C 315.1C T489C C522- A523- T710C A750G G1315A A1438G T1452C A1842G A1935G A2706G T3593C T4639C A4769G G5147A G5231A T6776C C7028T G7444A C7966T G8075A A8701G C8835T T8843C A8860G T9540C A10398G C10400T T10873C C11257T G11719A C12705T C13071A A13681G A13986G C14766T T14783C G15043A G15110A G15301A A15326G T16124C C16179A C16223T C16261T C16262T GQ337653 Palanichamy Haplogroup M 07-DEC-2015 A73G T152C A263G 315.1C G329A C522- A523- A750G T1040C A1438G G1719A A2706G A4769G T6216C A6770G C7028T A8860G T10027N A10028N A10029N C10030N T10031N A10032N G10033N T10034N T10035N T10036N T10037N G10038N A10039N C10040N A10041N A10042N C10043N A10044N T10045N T10046N C10047N A10048N A10049N A10050N A10051N A10052N A10053N G10054N A10055N G10056N T10057N A10058N A10059N T10060N A10061N A10062N A10063N C10064N T10065N T10066N C10067N G10068N C10069N C10070N T10071N T10072N A10073N A10074N T10075N T10076N T10077N T10078N A10079N A10080N T10081N A10082N A10083N T10084N C10085N A10086N A10087N C10088N A10089N C10090N C10091N C10092N T10093N C10094N C10095N T10096N A10097N G10098N C10099N C10100N T10101N T10102N A10103N C10104N T10105N A10106N C10107N T10108N A10109N A10110N T10111N A10112N A10113N T10114N T10115N A10116N T10117N T10118N A10119N C10120N A10121N T10122N T10123N T10124N T10125N G10126N A10127N C10128N T10129N A10130N C10131N C10132N A10133N C10134N A10135N A10136N C10137N T10138N C10139N A10140N A10141N C10142N G10143N G10144N C10145N T10146N A10147N C10148N A10149N T10150N A10151N G10152N A10153N A10154N A10155N A10156N A10157N T10158N C10159N C10160N A10161N C10162N C10163N C10164N C10165N T10166N T10167N A10168N C10169N G10170N A10171N G10172N T10173N G10174N C10175N G10176N G10177N C10178N T10179N T10180N C10181N G10182N A10183N C10184N C10185N C10186N T10187N A10188N T10189N A10190N T10191N A10316G A10398G T10609C C10877T G11719A T11944C G13359A C14766T A15326G G16129A G16145A T16249C T16288C C16301T T16304C T16311C T16519C GQ337654 Palanichamy Haplogroup M21 07-DEC-2015 A73G T152C A263G 315.1C T489C G709A A750G A1438G A2706G A3796G A4769G C7028T A8674G A8701G A8860G T9540C A10398G C10400T T10873C T11287C T11482C G11611A G11719A T11854C C11977T C12705T C14766T T14783C G15043A G15301A A15326G A15924G G16129A C16148T T16172C C16223T C16256T A16305G A16309G G16526A GQ337655 Palanichamy Haplogroup R21 07-DEC-2015 A73G T146C T152C T199C A249G A263G 309.1C 315.1C A750G A1438G G1709A G1719A C2397T A2706G C4711T A4769G C7028T T8279C A8860G A9067G T9077C A10398G A10610T A11404G G11719A A12234G C12510T G13145A C13293T C14766T A15326G A15613G C16168T C16295T C16296T T16304C T16519C

List A new LHON-cybrid mtDNA sequence has appeared on the GenBank database. The sequence is to accompany the paper (unpublished so far): Gomez-Duran,A., Hudson,G., Xu,Y., Santibanez-Koref,M., Ruiz-Pesini,E. and Chinnery,P.F. 'Mitochondrial transfer disrupts mTORC1/Akt signaling modulating biogenesis and respiration' which presumably will look at the link between the LHON mutation T14484C and mitochondrial biogenesis - whereby reduced biogenesis is linked to a higher incidence of visual loss, - whilst increased biogenesis preserves the vision. This paper might be quite interesting and I look forward to reading it. As usual I have added the sequence to my 'Checker' program to ensure accuracy of transcription. (But note the the FASTA file has the '3106-' marked with an 'M'.) Ian www.ianlogan.co.uk ---------------------- KT901801(cybrid) Gomez-Duran Haplogroup J2a2c 26-DEC-2015 A73G C150T T195C A263G C295T T310Y T489C A750G A1438G A2706G T3572Y T4216C A4769G T6671C C7028T G7269A C7476T A8860G A10398G A10499G A11002G A11251G G11377A G11719A A12570G A12612G G13708A T14484C G14569A C14766T G15257A A15326G C15452A A15679G C16069T T16126C T16231C

List Still catching up from Christmas !! Here are the latest FTDNA mtDNA sequences to appear on GenBank. The sequences were all submitted by customers who have chosen to make their own submissions. This service is still available - and there is no reason for interested people to not do this if they wish. The sequences belong to a variety of Haplogroups: 16 Dec 2015 Haplogroups H1a3, H3b2, H6a1a2b, H13a1a, H45a, T2b16 27 Dec 2015 Haplogroups H2a1, H5n, H17, I1a1, I2, I2c, T2b5, U3b1b, W1e And, as usual I have added the sequences to my 'Checker' program to ensure accuracy of transcription. Ian www.ian.logan.co.uk ------------------- KU240112(Sweden) FTDNA Haplogroup H1a3 16-DEC-2015 A73G A263G 315.1C A750G A1438G G3010A C4318A A4769G T5628C A8860G A15326G A16051G A16162G T16519C KU240113(Ireland) FTDNA Haplogroup H13a1a 16-DEC-2015 T146C A263G 309.1C 315.1C A750G A1438G C2259T A4745G A4769G G8764A A8860G C13680T C14872T A15326G KU240114(Finland) FTDNA Haplogroup H45a 16-DEC-2015 T199C A263G 315.1C A750G A1438G A4769G T8843C A8860G G9039A G12192A A15326G T16519C KU240115 FTDNA Haplogroup T2b16 16-DEC-2015 A73G A263G 309.1C 315.1C T634C G709A A750G G930A A1438G G1888A A2706G T4216C A4769G A4917G G5147A C7028T G8697A A8860G T10463C A11251G G11719A A11812G G13368A A14233G C14766T G14905A A15326G C15452A A15607G G15928A T16126C C16294T C16296Y T16304C T16362C T16519C KU252600(Sweden) FTDNA Haplogroup H6a1a2b 16-DEC-2015 T239C A263G 309.1C 315.1C A750G A1438G G3915A A4727G A4769G A7202G A8860G G9145A G9380A C9773T T11253C T11662C A15326G C16360T T16362C A16482G KU254157 FTDNA Haplogroup H3b2 16-DEC-2015 A263G 309.1C 315.1C A750G A1438G A2581G A4769G T6638C T6776C A8860G A15326G G16129A T16519C KU291098 FTDNA Haplogroup I1a1 27-DEC-2015 A73G T199C G203A T204C T250C A263G 315.1C 455.1T C522- A523- 573.1C 573.2C A750G A1438G G1719A A2706G A3447G C3990T A4529T A4769G G6734A C7028T G8251A G8616T A8860G G9947A T10034C T10238C A10398G T10915C G11719A G12501A C12705T T13404C A13780G C14766T G15043A A15326G C15789G A15924G G16129A T16172C C16223T T16311C G16391A T16519C KU291444(Scotland) FTDNA Haplogroup I2c 27-DEC-2015 A73G T152C T199C T204C G207A T250C A263G 315.1C 455.1T T460C 573.1C 573.2C A750G A1438G G1719A A2706G A4529T A4769G C7028T G8251A A8860G G9438A T10034C T10238C A10398G G11719A G12501A C12705T A13780G C14766T G15043A A15326G A15758G A15924G G16129A C16223T G16391A T16519C KU296183(Ireland) FTDNA Haplogroup T2b5 27-DEC-2015 A73G C151T T199C A263G 309.1C 315.1C G709A A750G G930A A1438G G1888A A2706G T3826C T4216C A4769G A4917G G5147A C7028T G7337A G8697A A8860G T10463C C11151T A11251G G11719A A11812G G12192A G13368A A14233G C14766T G14905A A15326G C15452A A15607G G15928A T16126C C16294T C16296T T16304C T16519C KU310655 FTDNA Haplogroup H5n 27-DEC-2015 G228A A263G 315.1C A373G C456T A750G A1438G A4769G A7004G G7598A A8489C A8860G A14893G A15326G T16093C T16304C KU310656(Ireland) FTDNA Haplogroup H17 27-DEC-2015 C256T A263G 315.1C A750G A1438G G3915A A4769G T7785C A8860G T11864C C12774T A15326G G16129A T16519C KU318667(Russia) FTDNA Haplogroup U3b1b 27-DEC-2015 A73G C150T A263G 309.1C 309.2C 315.1C A750G A1438G A1811G A2706G C3546A A4188G C4640A A4769G A6359G G6734R C7028T A8860G T8867C T9656C A11467G G11719A A12308G G12372A A12720G T13743C A14139G C14766T A15326G T15454C A16343G KU318668(France) FTDNA Haplogroup I2 27-DEC-2015 A73G T152C T199C T204C G207A T250C A263G 315.1C 573.1C 573.2C A750G A1438G G1719A A2706G A4529T A4769G C7028T G8251A A8860G T10034C T10238C A10398G G11719A G12501A C12705T A13780G C14766T G15043A A15326G A15758G A15924G G16129A C16223T G16391A G16474T T16519C KU323504(Germany) FTDNA Haplogroup W1e 27-DEC-2015 A73G T119C A189G T195C T204C G207A A263G 315.1C G709A A750G T1243C A1438G A2706G A3505G A4769G G5046A G5460A C7028T C7864T G8251A A8659G A8860G A8887G G8994A C11674T G11719A A11947G T12414C C12705T C14766T A15326G G15884C G16129A C16223T C16295T T16519C KU323505(Scotland) FTDNA Haplogroup H2a1 27-DEC-2015 C194T A263G 309.1C 315.1C A750G G951A C1833T T3150C A8860G T13326C A15326G C16354T

Linda, it is astonishing that any American genealogist would be interested only in American DNA matches--and especially not to be interested in Canadian matches! So many people have gone back and forth between the two areas (both before and after American independence), and so many immigrant families had some members settle in one country, some in the other. I'm an American with 7 of 8 great-grandparents being immigrants, and the 8th the son of immigrants. I have loads of Canadian relatives! At least one Norwegian great-aunt went north (so did one of her brothers, but he doesn't seem to have reproduced), lots of more distant Scottish relatives settled in Canada, and I'm sure some of the Germans did too. However, some of the DNA matches with all-colonial ancestry appear skeptical that ours is a useful match. If I were them, I'd be pleased to learn that the segment in common was Scottish (which is usually what it is). Karla On Fri, Jan 1, 2016 at 9:18 AM, Linda Reid via <genealogy-dna@rootsweb.com> wrote: > I agree completely with what Karla said about it being vital to test > cousins and that we should not expect our relatives to finance our hobby. > Like her, I've been pleasantly surprised when some have offered to pay > themselves and thrilled when they share their kit numbers and passwords > with me. In a couple of instances where non-keen genealogists have paid for > their own kits and not given me access or loaded to GEDmatch, I am very > frustrated and wish that I had paid for the test myself. We pay for > subscription databases, conference/workshop attendance, research trips-- > DNA tests are just another way of spending the money we are prepared to > devote to genealogical pursuits. I can't think of anything more productive > than testing the oldest generation still alive. If you don't have known > relatives in your match list to compare to, you are just spinning your > wheels guessing how matches might be related. > > If Americans are frustrated by discovering matches who don't know much > about their family trees, think about how much more frustrating it is to > non-Americans. I am a Canadian and my grandparents were all the immigrants: > two from England, one from Ireland and one from Scotland. I wish that there > was a marker on matches indicating "interested in US only". It would save > me so much time! If I had not been pro-active at getting relatives tested, > I would have got nothing from my Family Finder test. > > I have tested not only known close relatives but researched down > collateral lines to find more distant cousins. Finding and testing a 4th > cousin on my Irish line broke through a longstanding brick wall. > > > Message: 6 > Date: Thu, 31 Dec 2015 11:46:17 -0500 > From: Karla Huebner<calypsospots@gmail.com> > Subject: Re: [DNA] My First NPE > To: Lindsey Britton<lplantagenet@aol.com> > Cc:"genealogy-dna@rootsweb.com" <genealogy-dna@rootsweb.com> > Message-ID: > < > CA+FJH4NwZg0+WeCEwE4ozFvHqB4ccYYhKR4d5XSpJXs2n1Q14A@mail.gmail.com> > Content-Type: text/plain; charset=UTF-8 > > Testing cousins is vital. I'm always delighted when one of them is willing > to pay, but I figure I can't expect them to finance my hobby (even if > they're also into family history). > > Karla > > -- Karla Huebner calypsospots AT gmail.com