At least one branch of the Termini-Imerese Russo family has a serious inherited Thyroid problem (hypothyroidism). While not immediately life threatening, it can gradually cause serious illness. The symptoms always include extreme fatigue or a feeling of exhaustion and may also include weight gain, weight loss, depression, stomach cramps accompanied by chills, low blood pressure (in those with weight loss) or high blood pressure (in those with weight gain). The usual treatment for this problem, Synthroid, is barely effectual. The correct treatment must include BOTH T3 and T4 hormones. Levoxyl AND Cytomel are suggested. Siberian Ginseng Root helps to restore energy but has no effect on the low thyroid levels. The branch of the Russo family that suffers this problem includes Russo, Trentanella and DiMaria ancestors. See the Russo genealogy forum for details. Jim