Thanks Susan for the update on f3952! Sent from Samsung tablet -------- Original message -------- From: Susan Hedeen <chantillycarpets@earthlink.net> Date:05/08/2014 1:12 PM (GMT-05:00) To: dna-r1b1c7@rootsweb.com Subject: Re: [R-M222] Tree update A couple of questions -- and below that discussion of F3952 Do we have a list of which of the new sequenced SNPs are under investigation through YSEQ? -- in other words, I assume that all the ones listed on the tree have been sent over and Thomas has scrutinized and either ordered in primers or they are in the shop? Does anyone have access to Howard Lamont's Chromo2 positive variant page or better yet raw data file. I have been looking for a contact address and have sent message to Sandy -- is Sandy our contact on that one? Again, Iain, thank you kindly for your up-dates on these trees. In regard to Mitch's post regarding F3952 -- this SNP is under tested. Mitch's haplotype departs from McBride's as follows: 1 step up mutations at DYS - 439=13, 447=26, 531=12, 446=15 On DYS446 modal for the entire SNP confirmed set is 13; McBride has at 14. Statistically a mutation to either state on that allele in this data set is greater in incidence among the S588 down streams than with any of the other SNP defined groups. That said there are sporadic instances of mutation to either a 14 or 15 in some of the other groups on the other side of the tree, and the other groups are larger, so I do not believe we can trust the statistics here. 1 step down mutations at DYS 460=10, 607=15, 570=16, They split the difference at DYS 481; modal for the set is 25; Mitch =24 and McBride =26 McBride has a 1 step down mutation at 413a=20 McBride has a 1 step up mutation at 640=12 So there are 10 infinite allele counted mutations between them; with a correction for back mutations that calculates out as 44 generations to a common ancestor -- about 1100 years with a standard deviation amounting to 365 years because we don't have any other numbers to assess F3952 by we may not say with any certainty when it mutated away from S588; none the less with a spread like that between just 2 haplotypes we may assume that mutation occurred prior to that. Just a casual observation on the statistics...and don't take this too seriously because there are too few really to come to any conclusions on the matter really, but... DYS439 and possibly DYS 446 may mean something for the S588 and down stream possibles. As far as further testing goes, as mentioned above, this SNP is under tested and we yet no not any down streams from it. Sequencing efforts if possible may turn up some. My understanding is that even in JW's datathe F3952 confirmed tests number wise is not large, so statistically as it looks it may remain as a minority group -- but as also mentioned previously, the likely hood of testing bias probably exists resulting from choice to test. I would suggest that both Robert and Mitch begin surveying the data bases of M222 (don't neglect Mike's varieties) and see if you may ferret out some candidates to recommend testing to. Any other interested parties could do the same. Susan On 5/8/2014 9:17 AM, Iain Kennedy wrote: > I added the new S660 branches to the latest Wilson tree so that is more or less there now. > > http://www.kennedydna.com/M222_tree.png > > > > > > >> Date: Wed, 7 May 2014 12:39:41 +0100 >> From: pduffy81@gmail.com >> To: dna-r1b1c7@rootsweb.com >> Subject: Re: [R-M222] Tree update >> >> Iain, >> >> Great tree as always, any chance of an update on the SNP only tree at some >> stage: >> www.kennedydna.com/M222_tree.png >> >> Useful reference for SNP order etc. >> >> -Paul >> (DF41+) >> >> >> On Wed, May 7, 2014 at 12:37 PM, Iain Kennedy <ikennedy_msdn2@hotmail.com>wrote: >> >>> Somehow I missed Oliver Byrne 236891 who is S660/S659 on Chromo2 so I have >>> added him, with apologies. >>> >>> Is S660 going to overtake DF97?! >>> >>> Iain >>> >>> http://www.kennedydna.com/M222.pdf >>> >>> >>> >>> >>> >>>> From: ikennedy_msdn2@hotmail.com >>>> To: dna-r1b1c7@rootsweb.com >>>> Date: Tue, 6 May 2014 18:29:20 +0000 >>>> Subject: [R-M222] Tree update >>>> >>>> The latest version of the tree shows >>>> >>>> Steve Lominac has moved under FGC4087 >>>> Patrick J Byrnes #42289 has reported S590 from Chromo2 >>>> Male Kennedy (no STRs) is confirmed FGC4077- S661+ S588- DF85-. >>>> >>>> http://www.kennedydna.com/M222.pdf >>>> >>>> Iain >>>> >>>> >>>> >>>> >>>> >>>> >>>> ------------------------------- >>>> To unsubscribe from the list, please send an email to >>> DNA-R1B1C7-request@rootsweb.com with the word 'unsubscribe' without the >>> quotes in the subject and the body of the message >>> >>> >>> ------------------------------- >>> To unsubscribe from the list, please send an email to >>> DNA-R1B1C7-request@rootsweb.com with the word 'unsubscribe' without the >>> quotes in the subject and the body of the message >>> >> ------------------------------- >> To unsubscribe from the list, please send an email to DNA-R1B1C7-request@rootsweb.com with the word 'unsubscribe' without the quotes in the subject and the body of the message > > > ------------------------------- > To unsubscribe from the list, please send an email to DNA-R1B1C7-request@rootsweb.com with the word 'unsubscribe' without the quotes in the subject and the body of the message > ------------------------------- To unsubscribe from the list, please send an email to DNA-R1B1C7-request@rootsweb.com with the word 'unsubscribe' without the quotes in the subject and the body of the message