It is tough to know how much of this work for BigY results that FTDNA will do. For SNP confirmations, if the BigY shows trends w/ the M222, they well may develop single SNP tests for those SNPs and add to the single SNP testing program. If they do that, there may be no need to pursue Mark's option. That said, however, I know that FTDNA would likely vet whatever SNPs they develop a single SNP test for, and any trends would need to be assessed to make certain that they address the many rather than simply a few. It is a good approach slated by Mark and re-posted here, Linda, particularly for the FGC results...we might want to ask FTDNA if they have a game plan for the BigY assessment results or if they are depending on us to do the assessing. Susan On 11/22/2013 8:37 AM, Linda McKee wrote: > Folks with Full Y DNA results coming in may also want to consider the > following option from Mark Jost: > > > > MJost on Full Y DNA analysis > Posted at R1b-L21 Project at yahoo.com > > So, we, the Full Y DNA Testers have or are about to received our long > awaited results, and will soon discover that the journey is not finished > yet. More work will be needed. To further this process the individual > HaplogroupCompare" and other reports will be required for > cross-reference and other tasks. These reports will identify your novel > SNP(s) along with a number of "private" SNPs. Novel SNP(s) that are > derived, and also found in other datasets, either other FGC- L21er's > and/or are found in other major Y-DNA datasets. > > We all want our newly discovered SNP(s) placed on the Y-DNA Tree for all > to see. ISOGG now has the 'Final' word on the placement aspect. The > first step in this process is that ISOGG requests one derived sample to > be sequenced (=confirmed) with Sanger. This is one of several criteria > required for Tree placement. This is required to make sure that it's not > an artifact of the analysis method used. When this is confirmed, there > will be the need for more confirmations (other methods are considered > such as NGS results) from other kits within- and outside your Haplogroup > group to satisfy the other criteria. > > To assist in confirming validity for any new novel SNPs found in your > FGC reports by further conducting the Sanger testing, I am working with > a well known yet un-named "Expert" with this process who can produce the > primers and run the initial SNP testing required by ISOGG. This is a US > based company. > > I would like to coordinate the above process for my self and other FGC > Full Y testers. > > MJost > > In answer to my query for the M222+ folks with Full Y results: > > I am looking for the completed FGC result files that are sent to each > individual, for now. The file names contained are: > > VariantCompare > haplogroupCompare > gtype > > These files are contained along with others in a Zipped format. They can be > forwarded directly to me for review. > > I will then forward to the yet un-name company for their experts to verify > and create a primer and submit payment to validate the new novel SNP found > as the first step in the process of getting it on the ISOGG tree. From > these files I will be able to evaluate which other FGC returned kits > contain either an ancestral or derived states. Additional testing of others > maybe required. Example would be if you are currently DF13* and it reports > that four DF13 subclades indeed have the referenced ancestral allele, then > only the remaining ISOGG subclades will need to be tested. > > Remember these steps are needed to prove that the new novel SNP is valid > and further correctly placed on the Tree. > > MJost > > ------------------------------- > To unsubscribe from the list, please send an email to [email protected] with the word 'unsubscribe' without the quotes in the subject and the body of the message >