Had a comment from a member just now who indicated he was waiting for a sale to upgrade to 111 markers. And so wanted to share Debbie Kennett's excellent blog: ---------- Forwarded message ---------- From: Cruwys news <[email protected]> Date: Mon, Nov 18, 2013 at 1:05 AM Subject: Cruwys news To: [email protected] Cruwys news Family Tree DNA sale Posted: 17 Nov 2013 02:49 PM PST The Family Tree DNA sale is now on. It is not very easy to find a list of prices on the website so I've copied down all the prices here. The sale ends on 31st December and all tests must be paid for in full by this date. The prices below are shown in US dollars. You can convert the prices into your local currency using one of the many online currency converters. I normally use the XE Currency Converter. Note that the dollar/sterling exchange rate is particularly favourable at present for those of us in the UK! Basic tests for new customers Y-DNA 37 markers $119 (usual price $169) Y-DNA 67 markers $189 (usual price $268) Y-DNA 111 markers $289 (usual price $359) mtFull (full mitochondrial sequence) $169 (usual price $199) Family Finder $99 (US customers also receive a free $100 Restaurant.com gift certificate) Autosomal DNA Transfer $49 (usual price $69) - this allows people who have tested at 23andMe or AncestryDNA to transfer their autosomal results to FTDNA's Family Finder database Combination Tests Family Finder + Y-37 for $218 (usual price $268) Family Finder + Y-67 for $288 (usual price $367) Family Finder + mtFull for $268 (usual price $298) Y-37 + mtFull for $288 (usual price $366) Y-67 + mtFull for $358 (usual price $457) Comprehensive Genome (Family Finder, Y-67 and mtFull) for $457 (usual price $566) Upgrades Y-Refine 12 to 37 for $69 (usual price $109) Y-Refine 12 to 67 for $148 (usual price $319) Y-Refine 25 to 37 for $35 (usual price $59) Y-Refine 25 to 67 for $114 (usual price $59) Y-Refine 37 to 67 for $79 (usual price $109) Y-Refine 37 to 111 for $188 (usual price $220) Y-Refine 67 to 111 for $109 (usual price $129) mtHVR1 to Mega (full mitochondrial sequence) for $149 (usual price $169) Big Y This is a new Y-chromosome sequence test for advanced users who are interested in SNP discovery and contributing to our scientific knowledge about the phylogeny of the Y-chromosome. There is an introductory offer on this new test, and It is currently on sale for $495. This test is only available to existing customers. The price will go up to $695 after 1st December. If you have previously taken the Walk Through the Y test you will be eligible for a $50 discount. There should be a voucher that you can use on your personal page. For further information about the Big Y see my earlier blog post on the new Big Y test from Family Tree DNA. For information on the different types of DNA tests see the beginners' guides in the ISOGG Wiki. The Y-chromosome sequence interpretation service from YFull.com Posted: 17 Nov 2013 01:39 PM PST This article is for advanced genetic genealogists who have had their Y-chromosome sequenced or who are interested in doing so. With the forthcoming SNP tsunami, the analysis and interpretation of the Y-chromosome results provided by the various companies will be one of the key determining factors in the success of their products. Fortunately within the genetic genealogy community we have a number of intrepid pioneers who have volunteered to serve as guinea pigs by testing at all the companies so that we will eventually be able to do comparisons between all the products. David Hollister, who runs the Hollister one-name study and is the co-administrator of the Hollister DNA Project, is one of our brave guinea pigs. He has already had his Y-chromosome sequenced with Full Genomes Corporation. He has previously tested with the Genographic Project, and has had STR testing at Family Tree DNA. David is now waiting for his results from the Chromo 2 test from BritainsDNA and the BIG Y test from Family Tree DNA. Another genetic genealogist Itaï Perez has already provided a comprehensive look at the Full Genomes Y-sequencing results in a guest post on CeCe Moore's blog so I see no point in covering the same ground. However, David has recently submitted his Full Genomes data to another service by the name of YFull.com for an alternative interpretation. David was really excited by his results and was so "blown away" by the reports he received from YFull that I asked him if he might be able to share some screenshots so that other genetic genealogists might get a feel for what to expect from this service. David has very kindly agreed and has also obtained the consent of the YFull team for me to publish these screenshots. You will need to click on each image to see larger versions of the screenshots. This is David's home page on his YFull account. Note that according to YFull there are 41,828 known Y-SNPs and 478 short tandem repeats (Y-STRs). This report shows David's position on the Y-haplotree and his results for all the SNPs tested on his branch of tree. Separate reports are available for "controversial" SNPs and no calls. This report provides a list of private and unknown SNPs. 247 private and unknown SNPs were found in David's sequence: 66 were deemed to be of best quality, 10 were of acceptable quality, and 13 were of low quality. For 111 SNPs only one reading could be obtained. A temporary internal ID system is used to identify the private SNPs and they all bear the prefix YFS, an abbreviation for YFull Singleton. This report shows results for the Indels. Indel is the term used to describe insertions and deletions - positions in the sequence where extra As, Cs, Ts and Gs have been inserted or where they are absent. There is a handy SNP index that allows you to query your results by SNP name. Here is the report showing results for the 478 STRs tested. This pie chart shows the percentage of "good" and "uncertain" alleles. 90.2% of the alleles were classified as "good". Note that next generation sequencing with a read length of 100 bps does not pick up some of the longer STRs in the sequence. YFull have recently introduced a group feature. There are currently groups available for haplogroups R1a and G2a. YFull are based in Moscow in Russia. They are currently providing a free service for a limited period, but I understand that they will at some point start charging a small fee. They are able to use data for any Y-chromosome which has been sequenced at a minimum 25X coverage and with a read length of at least 100 base pairs. Data needs to be provided in the form of a BAM file. If you have tested with Full Genomes they will provide you with your BAM file on request. Results are not yet available from Family Tree DNA's BIG Y test but I understand that they will also make the BAM files available. It remains to be seen what level of analysis and interpretation FTDNA will provide. We can expect the interpretation of Y-chromosome sequencing results to change over time as our knowledge improves, and as more comparative results become available. In the meantime YFull certainly provides an interesting complement to the service provided by Full Genomes. No doubt we can expect other similar services to appear on the scene in the coming months as more sequences become available. See also - ISOGG Y-DNA SNP testing chart - The new Big Y test from Family Tree DNA - A confusion of SNPs - A simplified Y-tree and a common standard for Y-DNA haplogroup and SNP nomenclature © 2013 Debbie Kennett You are subscribed to email updates from Cruwys news To stop receiving these emails, you may unsubscribe now. Email delivery powered by Google Google Inc., 20 West Kinzie, Chicago IL USA 60610