Susan Maybe it's just me, but I find taking this extreme intrest in paternal genetics a bit creepy. The Scots have long been fascinated by the resurrectionists but this must be a new departure for the Irish. Malcolm Sent from a small screen (Spell-checker has mind of its one.) > On 14 Jun 2014, at 06:01 pm, John Loughney <john.loughney@gmail.com> wrote: > > If they are going through all of that trouble, why not do a Big Y test? > > Sent from my Lumia phone. > > -----Original Message----- > From: "Susan Hedeen" <chantillycarpets@earthlink.net> > Sent: ‎6/‎14/‎2014 5:48 PM > To: "dna-r1b1c7" <dna-r1b1c7@rootsweb.com> > Subject: Re: [R-M222] digging up the dead > > A quote from the approach: >> >> The principal objective of the Barrymore Project is to illuminate the >> origins and evolution of the Barry family, a prominent >> Anglo-Norman-Irish dynasty. To accomplish this, an effort is under >> way to conduct DNA testing of the remains of Richard Barry, 6th Earl >> of Barrymore, interred at Castlelyons >> <http://www.castlelyonsparish.com/history/churches-graveyards/castlelyons-graveyard/> in >> County Cork. >> >> The first step will be a detailed examination by forensic >> anthropologists of the several remains in the mausoleum. The initial >> goal will be to identify the biological sex, age-at-death and >> distinguishing physical characteristics of the individuals interred >> there, and to confirm that one set of remains is consistent with >> historical information about Richard Barry. Radio-carbon dating will >> also be employed to estimate the age of the remains. We will also >> document any salient points regarding the conditions of the remains >> and any light that can shed on his medical and personal history. >> >> Once the remains have been confirmed as those of Richard two samples >> will be taken for DNA analysis. The selection of the samples will be >> made at the time of examination, but teeth and the femur are two areas >> that have been identified as potential loci. >> >> The samples will be packaged securely, preserved, and shipped to two >> laboratories, one at University College Dublin and the second at Gene >> by Gene in Houston, Texas, USA. There the samples will be prepared >> for testing, and extraction of DNA will be undertaken. If DNA can be >> successfully isolated, the analysis can begin. >> >> While there is some passing interest in autosomal and mitochondrial >> DNA results, the principal focus is on paternal (YDNA) testing, since >> the male sex chromosome and the surname are passed down in tandem in >> Ireland. There are two types of desired results: >> >> * Short tandem repeat (STR) testing, which can provide data for >> comparing the results of this project with test results of other >> men with the Barry surname and for estimating the time to most >> recent common ancestor (TMRCA). >> * Single nucleotide polymorphism (SNP) testing, to assist in >> identifying the haplogroups (deep ancestry) of the individual >> whose remains are in the mausoleum, as well as his relationship to >> the other groups of Barry men for whom comparable results are >> available. >> >> The optimal result of the first test would be to obtain values for the >> 37 STR markers used in the YDNA test provided by Family TreeDNA >> <https://www.familytreedna.com/y-dna-compare.aspx>, a subsidiary of >> Gene by Gene that specializes in DNA testing for genealogy.Most of the >> 65 sets of results available for Barry men >> <https://dl.dropboxusercontent.com/u/44452288/Updated%20Report%20on%20Barry%20YDNA%20Project%2017%20Mar%201014.docx> >> are from this test, and the others are easily converted to that format. >> >> The Barry men who have tested fall into three major haplogroups, E, R >> and I and into several subclades (subgroups), defined by specific SNPS >> within those haplogroups. The SNPS of greatest interest are: >> >> E1b-M35.1 >> >> I-L22 >> >> I-M253 >> >> I2-L161 >> >> R1b-U106 >> >> R1b-Z49 >> >> R1b-L21. >> >> If the remains test positive for L21, then an attempt should be made >> to test for several L-21 subclades, specifically DF41_N, L159.2, L193, >> L643, L1066, *M222*, L144 and L195. It may be possible to narrow down >> the number of subclades if enough STR values are available to estimate >> the more likely ones. >> >> If the optimal levels of STR and SNP testing are not possible, some >> important conclusions could be drawn from less detailed results.For >> example, if results for the first 12 STR markers were available, the >> individual's major haplogroup could be estimated with a fair degree of >> confidence using available haplotype calculators.Also, modal haplotype >> for the various groups of Barry men who have tested are available for >> comparison.The number of markers in these haplotypes is generally 37, >> although some have as many as 111 markers, which would permit >> comparison with STRs other than those in the 37-marker test. If the >> lower level SNP tests are not possible, but some of the SNPS upstream >> of those listed above could be evaluated, then the major haplogroups >> and possibly some subclades could be identified. >> >> If these tests are successful, the results will be compared with those >> of other Barry men to determine their paternal relationships and >> documented in online reports and an article for peer review and >> publication. > > >> On 6/14/2014 12:37 PM, Susan Hedeen wrote: >> This article should interest folks. This is the marriage of the >> scientific and genetic genealogy aspects we all aspire to in the quest >> to sort out who may be be who and from whom they descend. >> https://sites.google.com/site/barrymorednaproject/home >> >> ------------------------------- >> To unsubscribe from the list, please send an email to DNA-R1B1C7-request@rootsweb.com with the word 'unsubscribe' without the quotes in the subject and the body of the message > > > ------------------------------- > To unsubscribe from the list, please send an email to DNA-R1B1C7-request@rootsweb.com with the word 'unsubscribe' without the quotes in the subject and the body of the message > > ------------------------------- > To unsubscribe from the list, please send an email to DNA-R1B1C7-request@rootsweb.com with the word 'unsubscribe' without the quotes in the subject and the body of the message