This article should interest folks. This is the marriage of the scientific and genetic genealogy aspects we all aspire to in the quest to sort out who may be be who and from whom they descend. https://sites.google.com/site/barrymorednaproject/home
A quote from the approach: > > The principal objective of the Barrymore Project is to illuminate the > origins and evolution of the Barry family, a prominent > Anglo-Norman-Irish dynasty. To accomplish this, an effort is under > way to conduct DNA testing of the remains of Richard Barry, 6th Earl > of Barrymore, interred at Castlelyons > <http://www.castlelyonsparish.com/history/churches-graveyards/castlelyons-graveyard/> in > County Cork. > > The first step will be a detailed examination by forensic > anthropologists of the several remains in the mausoleum. The initial > goal will be to identify the biological sex, age-at-death and > distinguishing physical characteristics of the individuals interred > there, and to confirm that one set of remains is consistent with > historical information about Richard Barry. Radio-carbon dating will > also be employed to estimate the age of the remains. We will also > document any salient points regarding the conditions of the remains > and any light that can shed on his medical and personal history. > > Once the remains have been confirmed as those of Richard two samples > will be taken for DNA analysis. The selection of the samples will be > made at the time of examination, but teeth and the femur are two areas > that have been identified as potential loci. > > The samples will be packaged securely, preserved, and shipped to two > laboratories, one at University College Dublin and the second at Gene > by Gene in Houston, Texas, USA. There the samples will be prepared > for testing, and extraction of DNA will be undertaken. If DNA can be > successfully isolated, the analysis can begin. > > While there is some passing interest in autosomal and mitochondrial > DNA results, the principal focus is on paternal (YDNA) testing, since > the male sex chromosome and the surname are passed down in tandem in > Ireland. There are two types of desired results: > > * Short tandem repeat (STR) testing, which can provide data for > comparing the results of this project with test results of other > men with the Barry surname and for estimating the time to most > recent common ancestor (TMRCA). > * Single nucleotide polymorphism (SNP) testing, to assist in > identifying the haplogroups (deep ancestry) of the individual > whose remains are in the mausoleum, as well as his relationship to > the other groups of Barry men for whom comparable results are > available. > > The optimal result of the first test would be to obtain values for the > 37 STR markers used in the YDNA test provided by Family TreeDNA > <https://www.familytreedna.com/y-dna-compare.aspx>, a subsidiary of > Gene by Gene that specializes in DNA testing for genealogy.Most of the > 65 sets of results available for Barry men > <https://dl.dropboxusercontent.com/u/44452288/Updated%20Report%20on%20Barry%20YDNA%20Project%2017%20Mar%201014.docx> > are from this test, and the others are easily converted to that format. > > The Barry men who have tested fall into three major haplogroups, E, R > and I and into several subclades (subgroups), defined by specific SNPS > within those haplogroups. The SNPS of greatest interest are: > > E1b-M35.1 > > I-L22 > > I-M253 > > I2-L161 > > R1b-U106 > > R1b-Z49 > > R1b-L21. > > If the remains test positive for L21, then an attempt should be made > to test for several L-21 subclades, specifically DF41_N, L159.2, L193, > L643, L1066, *M222*, L144 and L195. It may be possible to narrow down > the number of subclades if enough STR values are available to estimate > the more likely ones. > > If the optimal levels of STR and SNP testing are not possible, some > important conclusions could be drawn from less detailed results.For > example, if results for the first 12 STR markers were available, the > individual's major haplogroup could be estimated with a fair degree of > confidence using available haplotype calculators.Also, modal haplotype > for the various groups of Barry men who have tested are available for > comparison.The number of markers in these haplotypes is generally 37, > although some have as many as 111 markers, which would permit > comparison with STRs other than those in the 37-marker test. If the > lower level SNP tests are not possible, but some of the SNPS upstream > of those listed above could be evaluated, then the major haplogroups > and possibly some subclades could be identified. > > If these tests are successful, the results will be compared with those > of other Barry men to determine their paternal relationships and > documented in online reports and an article for peer review and > publication. > On 6/14/2014 12:37 PM, Susan Hedeen wrote: > This article should interest folks. This is the marriage of the > scientific and genetic genealogy aspects we all aspire to in the quest > to sort out who may be be who and from whom they descend. > https://sites.google.com/site/barrymorednaproject/home > > ------------------------------- > To unsubscribe from the list, please send an email to DNA-R1B1C7-request@rootsweb.com with the word 'unsubscribe' without the quotes in the subject and the body of the message >
If they are going through all of that trouble, why not do a Big Y test? Sent from my Lumia phone. -----Original Message----- From: "Susan Hedeen" <chantillycarpets@earthlink.net> Sent: 6/14/2014 5:48 PM To: "dna-r1b1c7" <dna-r1b1c7@rootsweb.com> Subject: Re: [R-M222] digging up the dead A quote from the approach: > > The principal objective of the Barrymore Project is to illuminate the > origins and evolution of the Barry family, a prominent > Anglo-Norman-Irish dynasty. To accomplish this, an effort is under > way to conduct DNA testing of the remains of Richard Barry, 6th Earl > of Barrymore, interred at Castlelyons > <http://www.castlelyonsparish.com/history/churches-graveyards/castlelyons-graveyard/> in > County Cork. > > The first step will be a detailed examination by forensic > anthropologists of the several remains in the mausoleum. The initial > goal will be to identify the biological sex, age-at-death and > distinguishing physical characteristics of the individuals interred > there, and to confirm that one set of remains is consistent with > historical information about Richard Barry. Radio-carbon dating will > also be employed to estimate the age of the remains. We will also > document any salient points regarding the conditions of the remains > and any light that can shed on his medical and personal history. > > Once the remains have been confirmed as those of Richard two samples > will be taken for DNA analysis. The selection of the samples will be > made at the time of examination, but teeth and the femur are two areas > that have been identified as potential loci. > > The samples will be packaged securely, preserved, and shipped to two > laboratories, one at University College Dublin and the second at Gene > by Gene in Houston, Texas, USA. There the samples will be prepared > for testing, and extraction of DNA will be undertaken. If DNA can be > successfully isolated, the analysis can begin. > > While there is some passing interest in autosomal and mitochondrial > DNA results, the principal focus is on paternal (YDNA) testing, since > the male sex chromosome and the surname are passed down in tandem in > Ireland. There are two types of desired results: > > * Short tandem repeat (STR) testing, which can provide data for > comparing the results of this project with test results of other > men with the Barry surname and for estimating the time to most > recent common ancestor (TMRCA). > * Single nucleotide polymorphism (SNP) testing, to assist in > identifying the haplogroups (deep ancestry) of the individual > whose remains are in the mausoleum, as well as his relationship to > the other groups of Barry men for whom comparable results are > available. > > The optimal result of the first test would be to obtain values for the > 37 STR markers used in the YDNA test provided by Family TreeDNA > <https://www.familytreedna.com/y-dna-compare.aspx>, a subsidiary of > Gene by Gene that specializes in DNA testing for genealogy.Most of the > 65 sets of results available for Barry men > <https://dl.dropboxusercontent.com/u/44452288/Updated%20Report%20on%20Barry%20YDNA%20Project%2017%20Mar%201014.docx> > are from this test, and the others are easily converted to that format. > > The Barry men who have tested fall into three major haplogroups, E, R > and I and into several subclades (subgroups), defined by specific SNPS > within those haplogroups. The SNPS of greatest interest are: > > E1b-M35.1 > > I-L22 > > I-M253 > > I2-L161 > > R1b-U106 > > R1b-Z49 > > R1b-L21. > > If the remains test positive for L21, then an attempt should be made > to test for several L-21 subclades, specifically DF41_N, L159.2, L193, > L643, L1066, *M222*, L144 and L195. It may be possible to narrow down > the number of subclades if enough STR values are available to estimate > the more likely ones. > > If the optimal levels of STR and SNP testing are not possible, some > important conclusions could be drawn from less detailed results.For > example, if results for the first 12 STR markers were available, the > individual's major haplogroup could be estimated with a fair degree of > confidence using available haplotype calculators.Also, modal haplotype > for the various groups of Barry men who have tested are available for > comparison.The number of markers in these haplotypes is generally 37, > although some have as many as 111 markers, which would permit > comparison with STRs other than those in the 37-marker test. If the > lower level SNP tests are not possible, but some of the SNPS upstream > of those listed above could be evaluated, then the major haplogroups > and possibly some subclades could be identified. > > If these tests are successful, the results will be compared with those > of other Barry men to determine their paternal relationships and > documented in online reports and an article for peer review and > publication. > On 6/14/2014 12:37 PM, Susan Hedeen wrote: > This article should interest folks. This is the marriage of the > scientific and genetic genealogy aspects we all aspire to in the quest > to sort out who may be be who and from whom they descend. > https://sites.google.com/site/barrymorednaproject/home > > ------------------------------- > To unsubscribe from the list, please send an email to DNA-R1B1C7-request@rootsweb.com with the word 'unsubscribe' without the quotes in the subject and the body of the message > ------------------------------- To unsubscribe from the list, please send an email to DNA-R1B1C7-request@rootsweb.com with the word 'unsubscribe' without the quotes in the subject and the body of the message