Hi Tim Thanks but does it keep to one side when matching[ all from the right side of the dna backbone or all from the left side of the dna backbone] or are some matches a mix, jumping between sides[taking some readings from the left and right of the dna segment] ? Karen On Sun, Jan 8, 2012 at 3:29 PM, Tim Janzen <[email protected]> wrote: > Dear Karen, > FF's program chooses from either side of the pair of alleles for a > match. > Sincerely, > Tim Janzen > > -----Original Message----- > From: [email protected] > [mailto:[email protected]] On Behalf Of Karen Hodges > Sent: Saturday, January 07, 2012 8:12 PM > To: [email protected] > Subject: [AUTOSOMAL-DNA] segment matches > > Does FF look at a string of bases down one side of the DNA backbone to > compare to find possible matches or does it look randomly, choosing from > either side of the pair [ A/T ,C/G]for a match? Sorry I don't know all the > technical terms to clearly ask this question. > > Karen > > > > ______________________________ > For answers to Frequently Asked Questions about mailing lists, please see: > http://dgmweb.net/MailingListFAQs.html > > > ------------------------------- > To unsubscribe from the list, please send an email to > [email protected] with the word 'unsubscribe' without > the quotes in the subject and the body of the message >
Dear Karen, No the program "doesn't keep to one side". Let's consider some imaginary data as follows for two people's comparison: #1 #2 AA AG GG GT TT TG AG GG AC CC TA AC GG TC Note that in the above example the program would indicate that the alleles for first 6 SNPs would be part of a half identical region (HIR) but the program would stop the HIR at the 7th SNP. Keep in mind that the raw data coming out of the SNP chip test is not phased. In other words, you can't tell which chromosome the allele is from simply by looking at the results. This is the reason why it is nice to phase the SNP chip data. However, the results from Family Finder and 23andMe are in the plus (or forward) strand orientation. See http://www.ks.uiuc.edu/Research/hemolysin/3versus5 and http://www.imgt.org/IMGTindex/dnaStrand.html for background on the strand orientation issue. Sincerely, Tim -----Original Message----- From: [email protected] [mailto:[email protected]] On Behalf Of Karen Hodges Sent: Saturday, January 07, 2012 9:28 PM To: [email protected] Subject: Re: [AUTOSOMAL-DNA] segment matches Hi Tim Thanks but does it keep to one side when matching[ all from the right side of the dna backbone or all from the left side of the dna backbone] or are some matches a mix, jumping between sides[taking some readings from the left and right of the dna segment] ? Karen